新入院精神分裂症患者兴奋激越症状的相关因素  被引量:17

Correlates of agitation in newly hospitalized patients with schizophrenia

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作  者:张素贞[1] 宓为峰[1] 刘琦[1] 李玲芝[1] 杨甫德[2] 王勇[3] 梅其一[4] 何红波[5] 陈致宇[6] 苏中华[7] 刘铁榜[8] 谢世平[9] 张聪沛 桑红[11] 张鸿燕[1] 

机构地区:[1]北京大学第六医院、北京大学精神卫生研究所、卫生部精神卫生重点实验室(北京大学),北京100191 [2]北京回龙观医院,北京100096 [3]上海市精神卫生中心,上海200030 [4]苏州市广济医院,江苏苏州215008 [5]广州市脑科医院,广州510370 [6]杭州市第七人民医院,杭州310007 [7]济宁市精神病防治院,山东济宁272051 [8]深圳市康宁医院,广东深圳518003 [9]南京脑科医院,南京210029 [10]哈尔滨第一专科医院,哈尔滨150056 [11]长春市心理医院,长春130052

出  处:《中国心理卫生杂志》2016年第12期881-885,共5页Chinese Mental Health Journal

摘  要:目的:调查新入院精神分裂症患者有兴奋激越症状的比例,探索兴奋激越症状发生的相关因素。方法:本研究为多中心、横断面研究。在11家医院纳入新入院(入院时间24 h内)的精神分裂患者,采用自编一般情况调查表、CGI-S、PANSS-EC和MOAS量表进行评估,其中PANSS-EC总分≥14分,且至少有一条目得分≥4分定义为激越,PANSS-EC总分≥20分定义为严重激越。结果:最终纳入1115例患者,其中717例(64.3%)有兴奋激越症状,346例(31.0%)有严重激越症状。多因素logistic分析显示,入院前一周明显攻击行为(OR=7.49,95%CI:5.58-10.07)、非自愿住院(OR=1.66,95%CI:1.162.36)和CGI-S评分高(OR=1.39,95%CI:1.151.69)是兴奋激越的危险因素。结论:本研究提示新入院精神分裂症患者有兴奋激越症状的比例可能较高,入院前一周有明显攻击行为是兴奋激越症状的重要因素。d Objective: To investigate the rate of agitation among newly hospitalized patients with schizophre- nia, and to explore possible risk factors related to agitation. Methods: It was a hospital-based survey study in 11 psychiatric hospitals. Information about agitation of all enrolled patients were assessed with a self-compiled ques- tionnaire about general demographic data and illness characteristics, the Clinical Global Impression-Severity (CGIS), Positive and Negative Syndrome Scale-Excited Component (PANSS-EC) and Modified Overt Aggression Scale(MOAS). Results: In the 1115 patients involved in the study, 717 (64. 3 % ) were agitated, and 346 (31.0% ) se- verely agitated. The related factor to agitation was the history of aggressive behavior ( OR = 7.49, 95% CI: 5.58 - 10. 07), higher CGI score (OR = 1.39,95% CI: 1.15 - 1.69) and involuntary hospitalization (OR = 1.66, 95% CI: 1.16 - 2. 36). Conclusions: The rate of agitation among newly hospitalized schizophrenic patients may be quite high, especially in those with history of aggressive behavior.

关 键 词:精神分裂症 兴奋激越 攻击 调查研究 

分 类 号:R749.3[医药卫生—神经病学与精神病学]

 

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