原发性肝脏腺鳞癌二例临床分析  

Primary adenosquamous carcinoma of liver： a clinical study of 2 patients

作　　者：董伟[1] 刘路 何坚男 肖卫东[1] 万真[1] 李勇[1] Dong Wei Liu Lu He Jiannan Xiao Weidong Wan Zhen Li Yong(Department of General Surgery, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Chin)

机构地区：[1]南昌大学第一附属医院普外科,330006 [2]浙江省舟山市普陀区人民,舟山316100

出　　处：《中华肝胆外科杂志》2016年第12期802-804,共3页Chinese Journal of Hepatobiliary Surgery

基　　金：江西省自然科学基金（2012BAB205095）;南昌大学研究生创新专项基金（cx2015190）

摘　　要：目的探讨原发性肝脏腺鳞癌（ASC）的临床诊断及治疗。方法回顾性总结分析2例经手术病理证实的原发性肝脏腺鳞癌的临床及病理资料。结果2例肿瘤均位于肝左叶。患者均有腹痛表现并行手术切除。大体病理肿块呈不规则形，边界不清。镜下示肿瘤细胞呈巢状排列伴有腺管状结构，呈腺鳞癌结构。1例术后存活4个月，另1例术后7个月死于肝内肿瘤复发。结论ASC的确诊仍需依赖病理，手术切除术是安全、可行的。Objective To study the diagnosis and treatment of primary adenosquamous carcinoma （ASC） of liver. Methods The clinical and histopathological data of 2 patients with ASC were analyzed retrospectively. The cases were confirmed by surgery and histopathological examination. Results The tumors were located in the left liver in these 2 patients. Both patients presented with abdominal pain and they underwent surgical resection. On gross pathological examination, the tumors were irregular in shape with unclear boundaries. Microscopically, the tumor cells were arranged in a nesting pattern with a tubular stru- cture, which was an adenosquamous carcinoma structure. One patient survived 4 months after surgery and the other patient died of intrahepatic tumour recurrence 7 months after surgery. Conclusions The diagnosis of primary hepatic ASC relied on histopathological examination. Surgical resection was safe and feasible.

关 键 词：肝脏肿瘤 腺鳞癌 免疫组化 诊断 治疗 

分 类 号：R735.7[医药卫生—肿瘤]