妊娠合并骨髓异常增生综合征1例  

Pregnancy associated with myelodysplastic syndrome: one case report

作　　者：吕小慧[1] 郭欣[2] 李佳[1] 周福兴[1] 刘朵朵[1] 刘淑娟[1] 陈必良[1] 

机构地区：[1]第四军医大学西京医院妇产科,陕西西安710032 [2]解放军第451医院腔镜外科,陕西西安710054

出　　处：《中国妇幼健康研究》2016年第11期1414-1415,共2页Chinese Journal of Woman and Child Health Research

基　　金：国家自然科学基金资助项目(编号:81402133)

摘　　要：骨髓增生异常综合征(MDS)是起源于造血干细胞的一组异质性髓系克隆性疾病,病理学表现为髓系细胞分化及发育异常,临床表现为无效造血、难治性血细胞减少、造血功能衰竭,高风险向急性髓系白血病(AML)转化。MDS治疗主要集中于两类问题:骨髓衰竭及并发症、AML转化。对于不同的患者而言,MDS患者自然病程和预后的差异性很大,治疗宜个体化。Myelodysplastic syndrome （ MDS） is a group heterogeneous of clonal myeloid disorders derived from hematopoietic stem cells . The pathological manifestations are abnormalities of myeloid cell differentiation and development .The clinical manifestations are ineffective hematopoiesis, refractory cytopenia, hematopoiesis failure and high-risk conversion to acute myeloid leukemia （AML）.The treatment of MDS mainly focuses on two points： bone marrow failure and complications as well as AML transformation .For different patients , the natural disease course and prognosis of MDS varies widely and the treatment should be individualized .

关 键 词：妊娠 骨髓异常增生综合征 病例报告 

分 类 号：R744[医药卫生—神经病学与精神病学]