急性淋巴细胞白血病VTP方案治疗效果观察  

Effect observation of VTP in the treatment of acute lymphoblastic leukemia

作　　者：刘慧卿[1] 

机构地区：[1]山东省寿光市人民医院血液风湿科,262700

出　　处：《中国实用医刊》2016年第23期26-28,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨急性淋巴细胞白血病VIP方案的治疗效果。方法选择2014年5月至2015年3月行VTP方案治疗的53例急性淋巴细胞白血病患者为研究组，另选择同期行VDP方案治疗的53例急性淋巴细胞白血病患者为对照组，治疗结束后对比两组的治疗效果以及不良反应发生情况。结果观察结果显示，VTP方案治疗急性淋巴细胞白血病患者的总有效缓解率为96．22％，显著高于VDP方案（64．15％），差异有统计学意义，（X^2=15．202，P〈0．01）；VDP治疗方案不良反应发生率为26．42％，显著高于VTP方案（5．66％），差异有统计学意义，（X^2=7．006，P〈0．01）。结论VIP方案治疗急性淋巴细胞白血病与VDP方案相比，治疗效果显著提高，而且不良反应明显减少。Objective To investigate the therapeutic effect of VIP on acute lymphoblastic leuke- mia. Methods A total of 53 cases of acute lymphocytic leukemia treated with VTP solution from May 2014 to March 2015 were selected as study group, and another 53 cases of acute lymphocytic leukemia who received VDP solution treatment during the same period and same hospital were selected as control group. The therapeutic effects and side effects of the two groups after treatment were compared. Results The total effective rate of the VTP regimen for patients with acute lymphocytic leukemia was 96. 22%, which was significantly higher than that of VDP solution（64. 15% ,X2 = 15.202, P 〈0. 01 ） ; the incidence of adverse reactions of the VDP treatment was 26.42%, which was significantly higher than that （5.66%） of VTP scheme （ X2 = 7.006, P 〈 0. 01 ）. Conclusions Compared with VDP solution, the effect of VIP regimen on acute lymphoblastic leukemia is significantly improved, and can reduce the side effects obviously.

关 键 词：白血病 VIP方案 治疗效果 

分 类 号：R733.71[医药卫生—肿瘤]