CT引导肺部恶性肿瘤RFA近期疗效及并发症  

Analysis of Complications and Treatment of CT-guided Radiofrequency Ablation of Lung Tumours

作　　者：关利君[1] 贾广志[1] 张春龙[1] 李晓光[2] GUAN Li-jun JIA Guang-zhi ZHANG Chun-long LI Xiao-guang(Department of Interventional Radiology, the Affiliated Hospital of Inner Mongolia Medical University, Huhhot 010050, China Tumor minimally invasive therapies center, Beijing Hospital, Beijing 100730, China)

机构地区：[1]内蒙古医科大学附属医院介入科,呼和浩特010050 [2]北京医院肿瘤微创治疗中心,北京100730

出　　处：《CT理论与应用研究（中英文）》2016年第6期687-694,共8页Computerized Tomography Theory and Applications

基　　金：吴阶平医学基金会临床科研专项资助基金(320675014268)

摘　　要：目的:探讨CT引导下肺部恶性肿瘤适形射频消融(RFA)近期疗效及并发症。方法:48例54个经病理证实的肺部恶性肿瘤在CT引导下行RFA,其中11个病灶联合化学消融治疗,通过临床观察和CT扫描监测并发症。术后1个月、3个月增强CT扫描观察近期疗效。结果:54个病灶RFA后即刻复查CT示病灶阴影增大,消融区域密度降低,术后1个月增强CT复查肿瘤去血管化表现,仅病灶边缘强化及肿瘤残留区域强化;54个病灶治疗后3个月复查增强CT,肿瘤完全消失(CR)61%(33/54),Ⅰ期24例,转移灶9个;肿瘤缩小(PR)39%(21/54),Ⅰ期1例、Ⅱ期16例、ⅢA期2例、2个转移病灶;无严重并发症发生。结论:CT引导肺部恶性肿瘤RFA是一种安全有效的微创治疗方法,近期疗效明显。Objective： To evaluate the value of CT-guided percutaneous RFA therapy of lung tumours and analyze complications. Methods： Fourty-eight patients with pathologically proved lung neoplasms that comprised 43 primary lung cancers initially underwent CT-guided percutaneous RFA treatment and subsequently the near-term efficacy. Results： Our experiments have indicated an initial increase in lesion size at immediate follow-up CT. The density of 54 lesions was lowered. Among total 54 lesions of 48 patients, RFA resulted in complete necrosis of 54 lesions, which appears as devascularization and enhancement of residual tumors on postcontrast CT images. Radiologically assessed through measurements of the lesions on axial CT scans in the lung window setting lesions had CR 61% （33/54） and PR 39% （21/54） at 3 month follow-up. No severe complications related to the procedure occurred in the group patients. Conclusion： CT-guided percutaneous RFA in treating lung neoplasms is safe and effective, which has recently received wide attention for the promising results achieved, and can serve as a new approach to the treatment of lung neoplasm.

关 键 词：肺 肿瘤 射频消融术 并发症 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]