汉族与维吾尔族不可复性牙髓炎一次性根管充填治疗后利多卡因镇痛效果对比研究  

Comparison study on the effect of lidocaine on reducing the postoperative pain after single-time root canal filling between Han and Uygur patients with irreversible pulpitis

作　　者：闫磊[1,2] 万娜[1] 王新迎[1] 尹艳娇 吴佩玲[1] YAN Lei WAN Na WANG Xin-ying YIN Yan-jiao WU Pei-ling(Department of Stomatology, Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830063, Chin)

机构地区：[1]新疆医科大学第二附属医院口腔科,新疆乌鲁木齐830063 [2]新疆军区总医院口腔科,新疆乌鲁木齐830000

出　　处：《中国实用口腔科杂志》2016年第11期685-688,704,共5页Chinese Journal of Practical Stomatology

摘　　要：目的通过临床对照试验,比较汉族与维吾尔族下颌第一或第二磨牙不可复性牙髓炎患者一次性根管充填治疗术后,应用利多卡因行下牙槽神经阻滞麻醉疼痛缓解的差异,为临床针对不同患者采取个性化治疗提供依据。方法选取汉族与维吾尔族下颌第一或第二磨牙不可复性牙髓炎患者各30例,均为新疆医科大学第二附属医院口腔科2016年1—6月9:00-13:00就诊的门诊患者。在根管治疗前应用含有1∶80 000肾上腺素的利多卡因注射液5 m L,实施患侧的下牙槽神经阻滞麻醉术,之后一次性完成根管预备和根管充填。治疗结束后,嘱患者若术后感觉疼痛无法承受,遵说明书服用布洛芬缓释胶囊并记录服药剂量与时间。患者需在术后6、12、24、36、48 h利用可视化痛觉量表(VAS)记录疼痛强度,在第5天复诊时交回问卷。所得数据分别利用Mann-Whitney秩和检验、卡方检验、Cochrane Q和t检验以及Pearson correlation进行统计学分析。结果根管治疗后6、12 h,汉族患者疼痛分值明显小于维吾尔族患者(P<0.05)。维吾尔族患者术后镇痛药物的服用量也多于汉族患者(P<0.05)。结论使用利多卡因进行下牙槽神经阻滞麻醉术的下颌磨牙不可复性牙髓炎患者中,维吾尔族患者较汉族患者更容易出现术后疼痛,疼痛程度也更为剧烈,维吾尔族患者会在一次性根充治疗后,倾向于服用更大剂量的镇痛药物。Objective To compare the different effect of lidocaine on reducing the postoperative pain as inferior alveolar nerve block anesthesia solution between Han and Uygur patients in first or second mandibular molar with irreversible pul- pitis after single-visit root canal treatment, in order to provide a better basis for personalized clinical administration. Methods In this clinical controlled experiments, 30 Han and 30 Uygur patients were selected, whose first or second mandibular molar was diagnosed with irreversible pulpitis, and received 2% lidocaine with 1 ： 80 000 epinephrine as the anesthetic solutions for inferior alveolar nerve blocks before single-visit root canal treatment. Each patient was asked to record their pain score on a visual analogue scale （VAS）at 6, 12,24 and 48 hours after treatment. Patients were instruct- ed that they could use analgesics （ibuprofen 300mg, Xiehe Pharmaceutical Co. Ltd., every 6 hours）if they felt intolerable pain. Data were analyzed by Mann-Whitney test, χ^2 test, Cochrane Q and T tests as well as Pearson correlation analysis. Results The experimental data showed that postoperative pain scores of the Han patients were significantly lower than Uygur patients＇scores（P 〈 0.05）at 6 -12 h after single-visit root canal treatment. The use of analgesia drug in Han patients was also less than Uygur patients （P 〈 0.05）. Conclusion Han patients who receive lidocaine as anesthetic solution before single-visit root canal treatment for irreversible pulpitis in first or second mandibular molars have significantly less postoperative pain and use fewer analgesics than Uygur patients.

关 键 词：利多卡因 下牙槽神经阻滞麻醉术 根管治疗 术后疼痛 维吾尔族 

分 类 号：R78[医药卫生—口腔医学]