双能量CT成像评估胃癌分化程度的价值  

Value of dual-energy CT scan for evaluation of differentiation grade of gastric cancer

作　　者：万娅敏[1] 高剑波[1] 王芳[1] 陈岩[1] 梁盼[1] 

机构地区：[1]郑州大学第一附属医院放射科,郑州450052

出　　处：《放射学实践》2016年第12期1210-1212,共3页Radiologic Practice

基　　金：河南省高等学校重点科研项目计划(14A320033)

摘　　要：目的:探讨双能量CT成像对评估胃癌分化程度的价值。方法:2012年12月-2014年12月本院41例胃癌患者行双源CT双能量腹部双期增强扫描,测量100、120和140kV图像及40~140keV各单能量图像(共14组图像)上胃癌病灶在动脉期和门静脉期图像上的CT值,并计算静脉期与动脉期CT值的差值(△CT)。利用t检验分析中高分化胃癌与低分化胃癌间CT值及△CT值的差异。结果:中高分化胃癌与低分化胃癌在各组中动脉期、静脉期图像上CT值的差异均无统计学意义(P>0.05);在120、140kV以及80~130keV图像上,中高分化胃癌与低分化胃癌间△CT的差异有统计学意义(P值分别为0.043、0011、0.035、0.016、0.013、0.017、0.030和0.046)。结论:双源CT双能量增强扫描有助于评估胃癌的分化程度。Objective：To explore the value of dual-energy CT scan for evaluating differentiation grade of gastric cancer. Methods：Between December 2011 and December 2012,41 patients with gastric cancer proved by pathology were included in the study. All patients underwent dual phase （arterial phase and portal phase） contrast-enhanced scanning using dual-energy technique at dual-source CT. Images of 14 groups were obtained including 100,120 and 140kV conventional images and 40-140keV single-energy images. In each group, CT attenuation values of the tumors in the arterial phase （CTA） and portal phase （CTP） were measured, ACT （CTP-CTA） was calculated, and the difference of CT and ACT between well to moderately and poorly differentiated carcinoma was analyzed using t test. Results：In each group, there were no differences of the CT values in arterial phase and portal phase between well to moderately and poorly differentiated carcinoma （P^0.05）. There was significant difference of ACT between well to moderately and poorly differentiated carcinoma on the 120 and 140kV images and monochromatic images from 80 to 130keV （P=0. 043,0011,0. 035,0. 016,0. 013,0. 017,0. 030 and 0. 046）. Conciusion：Using contrast-enhanced dual-energy CT scanning is helpful to evaluating the differentiation grade of gastric cancer.

关 键 词：胃肿瘤 CT值 体层摄影术 X线计算机 双能量扫描 双期增强扫描 

分 类 号：R735.2[医药卫生—肿瘤] R814.42[医药卫生—临床医学]