组织胶联合聚桂醇治疗胃底静脉曲张的临床疗效分析  被引量:4

Clinical Efficacy of Tissue Adhesive Combined with Lauromacrogol in the Treatment of Gastric Varices

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作  者:李亚岭[1] 罗建平[1] 

机构地区:[1]黄河水利委员会黄河中心医院消化内科,河南郑州450003

出  处:《中外医疗》2016年第34期148-150,共3页China & Foreign Medical Treatment

摘  要:目的探讨组织胶联合聚桂醇治疗胃底静脉曲张的临床疗效。方法方便选取80例2014年2月—2016年3月间该院收治的胃底静脉曲张患者,并随机分成研究组和对照组。研究组40例,以组织胶联合聚桂醇治疗,对照组40例,研究组患者在胃镜直视下依次注射碘化油、聚桂醇、组织胶、碘化油,对照组患者不注射聚桂醇,其他操作同研究组。比较两组患者手术过程中GV缓解时间、GV消失时间、再出血时间、止血成功率、术后1个月溃疡面积以及再出血率,比较组间差异。结果 1研究组GV缓解时间、消失时间、再出血时间显著少于对照组,1个月后溃疡面积(4.4±2.0)cm2显著大于对照组(1.8±1.1)cm2,差异有统计学意义,t=3.635、4.368、4.617、7.247,P<0.05。2两组患者止血成功率、死亡率、并发症发生率差异无统计学意义,P>0.05;但研究组再出血率明显低于对照组,χ2=2.728,P<0.05,差异有统计学意义。结论组织胶联合聚桂醇治疗胃底静脉曲张疗效显著,再出血几率低,安全可靠,值得临床推广应用。Objective To investigate the clinical efficacy of tissue adhesive combined with lauromacrogol in the treatment of gastric varices. Methods Convenient selection 80 cases of patients with gastric varices who were treated in our hospital from February 2014 to March 2016, were randomly divided into study group and control group. 40 cases for each goup. Patients in the study group were taken under the gastroscope sequentially iodized oil injection, tissue adhesive and lauromacrogol,iodized oil, while the control group were injected with the same medicine as the study group except lauromacrogol. Compared the GV remission time, GV disappear time, the bleeding time, the success rate of hemostasis, one month after the ulcer area and re bleeding rate of patients in the two groups. Results 1the remission time, disappearance time and bleeding time of the study group were significantly less than those of the control group, and the area of ulcer(4.4±2.0)cm2was significantly larger than that of the control group(1.8±1.1)cm2after one month, the difference was statistically significant, t =3.635, 4.368, 4.617, 7.247,P0.05. 2there was no significant difference in hemostasis success rate, mortality rate and incidence of complications between the two groups, P〉0.05; but the rate of re bleeding in the study group was significantly lower than that in the control group, χ2=2.728, P0.05, and there was significant difference. Conclusion The effect of tissue adhesive combined with lauromacrogol in the treatment of gastric varices is significant, and it is safe and reliable,which is worthy of clinical application.

关 键 词:胃底静脉曲张 组织胶 聚桂醇 再出血 

分 类 号:R575.2[医药卫生—消化系统]

 

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