屈光不正儿童干眼症治疗方法的临床研究  

Clinical study on the treatment of dry eye in refractive error children

作　　者：郭元懿[1] 陶军[1] 

机构地区：[1]沈阳市第四人民医院眼科,沈阳110031

出　　处：《中国实用眼科杂志》2016年第12期1257-1260,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的了解屈光不正儿童干眼症的特点，探讨屈光不正儿童干眼症的治疗方法。方法临床病例对照研究。对2014年9月至2015年12月在沈阳市第四人民医院眼科就诊，诊断为屈光不正的且符合干眼诊断标准的儿童270例按屈光状态分为轻度近视组、轻度远视组和轻度散光组，每组各90例，并对每组按自愿原则分为屈光矫正＋药物治疗组，屈光矫正组、药物治疗组。对各组患儿治疗前，治疗后3个月的Schirmer Test（泪液分泌试验）、BUT（泪膜破裂时间）、FL（角膜荧光素染色）进行检查。同时选取60例正视眼儿童作为对照组。结果治疗前轻度散光组BUT明显小于轻度近视和轻度远视组，轻度远视组BUT明显小于轻度近视组，差异有统计学意义（P〈0．05）。治疗后3个月各组的BUT与治疗前相比均明显延长，差异有统计学意义（P〈0．05）。其中屈光矫正＋药物治疗组BUT延长最明显，其次是屈光矫正组，差异有统计学意义（P〈0．05）。在屈光矫正组中散光组的治愈率最高，其次是远视组。差异有统计学意义（P〈0．05）。结论屈光不正儿童的干眼症主要表现为BUT（泪膜破裂时间）缩短。针对这类患儿首先应矫正屈光不正，屈光矫正＋药物治疗是最佳的治疗方法。Objective To investigate the characteristics of children with ametropia of dry eye, ex- plore the method of treatment for children with ametropia of dry eye. Methods A clinical case con- trol study was adopted. Form September 2014 to September 2015 in Shenyang the Fourth Hospital of People for treatment, diagnosis for ametropia and accord with dry eye diagnosis standard of the children 270 cases, according to the refractive status points for mild myopia group and mild hyper- metropia group and mild astigmatism group, 90 cases in each group. Each group was according to the voluntary principle for refractive correction ＋ drug treatment group, refractive correction group and drug treatment group. Schirmer test （Schirmer test）, BUT （break-up time）, FL （corneal fluoresce- in staining） of the children in these groups were checked before treatment and 3 months after treat- ment. At the same time, 60 cases of emmetropic eye children were selected as control group. Re- sults Before treatment, BUT of mild astigmatism group was significantly less than mild myopia and mild hypermetropia group, BUT of mild hypermetropia group was significantly less than mild myo- pia group, P 〈0.05, the difference was statistically significant. After 3 months of treatment, the BUT of each group was significantly longer than that before treatment, and the difference was statistically significant. Among them, BUT of refractive correction ＋ drug treatment group was the most obvi- ous, followed by refractive correction group, the difference was statistically significant. Astigmatism group were the highest cure rate in refractive correction treatment group, followed by the hyperopia group. The difference was statistically significant. Conclusions The main symptoms of dry eye in Children with ametropia is BUT （tear break-up time） shortened. For these children should first cor- rect refractive error, refractive correction ＋ drug treatment is the best treatment.

关 键 词：儿童 屈光不正 干眼 

分 类 号：R778.1[医药卫生—眼科]