口腔微生物群落结构与临床疾病相关性的研究进展  

Research progress on the oral microbial community structure and its correlation with clinical diseases

作　　者：刘静[1] 张欣[1] 李志艳[2] 赵翀[2] 陈筠[2] 朱德锐[1] 

机构地区：[1]青海大学医学院基础医学研究中心,青海西宁810016 [2]青海大学附属医院,青海西宁810016

出　　处：《牙体牙髓牙周病学杂志》2016年第12期747-751,共5页Chinese Journal of Conservative Dentistry

基　　金：国家自然科学基金(31560039);青海省基础研究计划项目(2014ZJ759&2015ZJ929Q)

摘　　要：人类口腔内栖息有多种微生物,包括细菌、古细菌、真菌和病毒,其与龋损、牙周炎、根尖周炎、口臭、菌血症、心血管系统疾病、糖尿病、肥胖以及不良妊娠等诸多疾病的发生密切相关。本文就口腔微生物种群多样性和种群结构以及微生物可能引起疾病发生的相关性作一综述。Many kinds of microorganisms including bacteria, archaea, fungi and viruses, inhabit in the human oral cavity and they are closely related to the occurrence of oral diseases such as dental caries, periodontal disea- ses, periapical infection, halitosis, bacteremia and systematic diseases such as cardiovascular disease, diabetes mellitus, obesity and adverse pregnancy outcomes. In this review, the diversity and structure of oral microorganisms are systematically reviewed and the potential correlation of oral microbes with these diseases is discussed.

关 键 词：口腔微生物 种群结构 临床疾病 致病性 

分 类 号：R780.2[医药卫生—口腔医学]