非典型阴茎雀斑样痣1例  

A Case of Atypical Penile Lentigo

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作  者:王琳[1] 邵莉梅[1] 刘静[1] 张广富[1] WANG Lin SHAO Li-mei LIU Jing ZHANG Guang-fn(Department of Dermatology of People's Hospital, Huaibei 235000, Chin)

机构地区:[1]安徽省淮北市人民医院皮肤科,安徽淮北235000

出  处:《中国皮肤性病学杂志》2017年第1期69-70,共2页The Chinese Journal of Dermatovenereology

摘  要:患者男,23岁。阴茎龟头黑褐色斑片5年余。皮损组织病理检查示:表皮基底层黑素和黑素细胞增生,部分区域呈连续性分布,个别黑素细胞向表皮上部扩散,可见黑素细胞异型改变,真皮浅层多数淋巴细胞、噬色素细胞浸润。免疫组织化学(SP法)示:S-100(2+)、HMB-45(3+)、Melan-A(3+)、Ki-67:10%细胞阳性。诊断:非典型阴茎雀斑样痣。A 23-year-old man with atypical penile lentigo was reported. The patient presented with asymptomatic pig mented lesions on the glans penis for about 5 years. Histopathological examination showed melanocytic hyperplasia and melanin increasing were seen in the basal cell layer, with partly continuous distribution. A few of melanocytes spread into superfical epidermis and heterotypic melanocytes was observed. The dermis contained lymphocytes and melauophages. Immunohistochemical staining showed positive for S-100, HMB-45, Melan-A and Ki-67. Finally, it was diagnosed as atypical penile lentigo according to clinical manifestation, histopathological and immunohistochemical features.

关 键 词:雀斑样痣 非典型 阴茎 

分 类 号:R739.5[医药卫生—肿瘤]

 

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