破骨细胞蛋白酪氨酸磷酸酶与正畸移动牙牙根吸收的关系  

The relationship between osteoclastic protein-tyrosine phosphatase and orthodontic treatment induced root resorption

作　　者：崔跃[1] 姜欢[1] 胡敏[1] Cui Yue Jiang Huan Hu Min.(Dept. of Orthodontics, Hospital of Stomatology, Jilin University, Changchun 130021, China)

机构地区：[1]吉林大学口腔医院正畸科,长春130021

出　　处：《国际口腔医学杂志》2017年第1期87-91,共5页International Journal of Stomatology

基　　金：国家自然科学基金(81470764)~~

摘　　要：牙根吸收是正畸治疗过程中一种常见的并发症,影响正畸牙牙根吸收的因素十分复杂。牙根吸收的过程与骨吸收过程相似,由与破骨细胞形态相似功能相仿的破牙骨质细胞发挥主要作用。破骨细胞蛋白酪氨酸磷酸酶(PTP-oc)主要在破骨细胞中表达,且对破骨细胞具有正调节作用。本文探讨PTP-oc的作用机制,旨在为防治牙根吸收提供一定的参考依据。Root resorption is a common complication of orthodontic treatment whose factors are very complicated. The processe of root resorption is similar to bone resorption. The cementoclast plays a main role in this process, and it is similar to the shape and function of osteoclasts. Osteoclastic protein-tyrosine phosphatase（PTP-oc） is mainly expressed in osteoclasts, and has a positive regulatory effect on osteoclasts. In this paper, the mechanism of PTP-oc is discussed, which provides a reference for the prevention and treatment of root resorption.

关 键 词：牙根吸收 破骨细胞蛋白酪氨酸磷酸酶 作用机制 

分 类 号：R783.5[医药卫生—口腔医学]