有晶状体眼后房型人工晶状体植入术后拱高的变化及相关影响因素  

Changes in the central vault after collamer lens implantation and its impact

作　　者：徐婧[1,2] 罗岩[1] 林燕楠 李莹[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院眼科,100730 [2]首都医科大学附属北京天坛医院眼科,100050

出　　处：《中华眼视光学与视觉科学杂志》2016年第12期714-718,共5页Chinese Journal Of Optometry Ophthalmology And Visual Science

摘　　要：目的探索有晶状体眼后房型人工晶状体（PPC-ICL）植入术后1年拱高的变化趋势及相关的影响因素。方法回顾性系列病例研究。纳入因高度近视接受PPC—ICL植入手术患者69例（134眼），术后随诊时间大于1年。应用光学相干断层扫描（OCT）前节程序检查患者术后1个月和1年时的拱高和瞳孔直径，并分析瞳孔直径、白到白距离（WTW）、PPC-ICL度数和PPC-ICL长度影响拱高的程度。数据采用重复测量方差分析和多元回归分析。结果患者术后1个月拱高112～1131μm．平均（576±247）μm；术后1年拱高159～1168μm，平均（512±238）μm，术后1年和术后1个月相比，拱高减小-210～135（65±85）μm（F=7．11，P〈0．01）。回归模型显示，术后1个月、1年拱高与等效球镜度呈负相关，与PPC-ICL度数和PPC-ICL长度呈正相关（调整R2=0．389、0．434，F=17．75、21．15，P〈0．01）。回归模型显示，术后1年WTW越大，拱高减少越明显，而PPC-ICL长度和拱高变化呈负相关，PPC-ICL长度越大，拱高的变化越小（调整R2=0．500，F=7．99，P〈0．05）。结论PPC-ICL植入术后1年内拱高有减小趋势。拱高大小受患者等效球镜度、PPC-ICL度数和长度的影响，拱高变化量受WTW和PPC-ICL长度影响。Objective To investigate changes in the central vault one year after collamer lens （PPC-ICL） implantation surgery and its impact factors. Methods This retrospective study included 134 eyes of 69 patients. Mean spherical equivalent （SE） was -12.28±3.80 diopters （D） （range： -5.00 to -20.50 D） for those who underwent PPC-ICL implantation. In addition to a complete ophthalmologic examination, the central vault was measured with Topcon OCT and evaluated during the follow-up period （1 month to 1 year, postoperatively）. Data were analyzed using repeated measures ANOVA, muhiple linear regression analysis. Results Within the first year, the mean central vault dropped from 576±247μm （range 112 to 1 131 μm） to 512±238 μm （range 159 to 1 168 μm）. This decrease was significant by 65±85 μm （range -210 to 135μm） （F=7.11, P〈0.01） within this period. Regression fomula showed 1 month and 1 year postoperation vault was negative related with SE, but positive related with diopter and overall length of the PPL-ICL （R2=0.389, 0.434, F=17.15, 21.15, P〈0.01）. White-to-white （WTW） diameter and the overall length of the PPC-ICL （R2=0.500, F=7.99, P〈0.05） were factors that were significantly associated with a decrease in the vault between 1 year and 1 month postoperation. Conclusion A significant reduction in the central vauh occurred from 1 month to 1 year, postoperatively. The decrease in the vault was more pronounced in eyes with a larger WTW and a smaller overall diameter.

关 键 词：近视 退行性 有晶状体眼人工晶状体植入术 体层摄影术 光学相干 拱高 

分 类 号：R779.6[医药卫生—眼科]