大黄煎剂保留灌肠治疗轻微型肝性脑病  

TCM Mechanism of Dahuangjianji retention enema treating minimal hepatic encephalopathy

作　　者：杨小徽[1] 黄国初[2] 王萌[2] 姚凡[2] 钟宇[2] 姚春[1] 

机构地区：[1]广西中医药大学,南宁530001 [2]广西中医药大学第一附属医院,南宁530023

出　　处：《吉林中医药》2016年第12期1220-1222,共3页Jilin Journal of Chinese Medicine

基　　金：国家自然科学基金项目(81160439)

摘　　要：轻微型肝性脑病是肝性脑病的一个特殊类型,归属于中医"神昏""郁证""失眠""便秘"等范畴,其关键病机为"痰、瘀、毒"互结,以致腑气不通,脑窍蒙蔽,瘀毒内积;使用通腑开窍,解毒导滞之法,可将肠道毒浊之气排出体外,以达开窍醒神之功。大黄煎剂(大黄30 g,乌梅30 g)具有通腑开窍,解毒导滞之功,使用大黄煎剂保留灌肠可清除内毒素、降低血氨,对轻微型肝性脑病有治疗作用。探讨大黄煎剂治疗轻微型肝性脑病的中医机制有利于评价中医药临床疗效,为临床诊治轻微型肝性脑病提供理论依据并拓宽思路。Minimal Hepatic Encephalopathy is a special type of hepatic encephalopathy,which belonging to Chinese medicine ＂unconsciousness＂,＂depression＂＂insomnia＂＂constipation＂and some other related TCM syndromes.The key pathogenesis of MHE is phlegm,blood stasis and toxin mutual interleaving together which caused the obstruction of Fu Qi,brain unconscious and toxin product accumulation. The use of purgation and resuscitation,and stagnation of the method,the bowel poison polluted gas discharged out of the body,to achieve the resuscitative effect.Dahuangjianji（ rhubarb30 g,ebony 30 g） retention enema which having the effect of treating MHE by removing endotoxin and reducing the blood ammonia. To explore TCM mechanism of Dahuangjianji retention enema in the treatment of MHE is conducive to the evaluation of the clinical efficacy of Chinese medicine,for clinical diagnosis and treatment of MHE provide theoretical basis and broaden our thinking.

关 键 词：大黄煎剂 保留灌肠 外治法 轻微型肝性脑病 

分 类 号：R575.2[医药卫生—消化系统]