肝动脉化疗栓塞联合微波消融和无水乙醇消融治疗巨块型肝癌的疗效分析  

An Analysis on Curative Effect of Treating Massive Hepatocarcinoma by Hepatic Arterial Chemoembolization Combined with Microwave Ablation and Absolute Ethanol Ablation

作　　者：郑玉劲[1] 吴庆德[1] 蒙立艳[1] 

机构地区：[1]广州中医药大学附属顺德中医院放射科,顺德528333

出　　处：《临床放射学杂志》2016年第12期1885-1888,共4页Journal of Clinical Radiology

基　　金：2014年佛山市医学科技攻关项目(编号:2014AB002183)

摘　　要：目的分析肝动脉化疗栓塞术(TACE)联合微波消融(PMCT)和无水乙醇瘤内注射术(PEI)治疗巨块型肝癌的临床疗效。方法回顾性总结接受TACE联合PMCT和PEI治疗的16例(30个肿瘤)无法手术切除的巨块型肝癌患者。最大病灶直径均>10 cm,随访分析局部疗效和长期生存率。结果所有患者的联合治疗成功率为100%(30/30),30个肿瘤完全灭活率为93.3%(28/30),并发症发生率为6.25%(1/16)。局部及远处复发率分别为16.6%(5/30)和75%(12/16),1、2年无瘤生存率分别为31.2%(5/16)、18.8%(3/16),1、2、3年总生存率分别为87.5%(14/16)、43.7%(7/16)、18.7%(3/16),中位生存期为15.0个月。结论 TACE联合PMCT和PEI治疗巨块型肝癌是安全、有效、可行的方法。Objective To analyze the clinical efficacy of transcatheter arterial chemoembolization（ TACE） combined with percutaneous microwave coagulation therapy（ PMCT） and percutaneous ethanol injection（ PEI） in the treatment of massive hepatocarcinoma. Methods Follow up local curative effect and long-term survival rate of 16 cases of patients that were treated by TACE combined with PMCT and PEI from February 2013 to July 2015 in our hospital,whose massive hepatocarcinomas could not be excised and the maximum diameter of the diseases of all patients were 10 cm. Results The success rate was 100%（ 30 /30） and the total inactivation rate of tumor was 93. 3%（ 28 /30）. Furthermore,the incidence of complications was 6. 25%（ 1 /16）. At the same time,local and distant recurrence rates were,in respective order,16. 6%（ 5 /30） and 75%（ 12 /16）,and l or 2 years without tumor survival was 31. 2%（ 5 /16）,18. 8%（ 3 /16）,respectively. The overall survival rates of 1,2,and 3 years were 87. 5%（ 14 /16）,43. 7%（ 7 /16）,18. 7%（ 3 /16） respectively,and the median survival time was 15 months. Conclusion TACE combined with PMCT and PEI in the treatment of massive hepatocarcinoma is a safe,effective and feasible method.

关 键 词：肝肿瘤 巨块型 微波消融 动脉栓塞 经皮酒精注射 

分 类 号：R735.7[医药卫生—肿瘤]