柴胡疏肝散加味联合熊去氧胆酸治疗急性结石性胆囊炎患者的疗效观察  

The effect of Chaihu shugan decoction combined with ursodeoxycholic acid on the treatment of cholecystitis

作　　者：杨振林[1] 姚春和[1] 傅金坤 李金燕[1] 李晖[2] 

机构地区：[1]延安大学咸阳医院,咸阳712000 [2]陕西省人民医院肝胆外科,西安710068

出　　处：《广西医科大学学报》2017年第1期77-79,共3页Journal of Guangxi Medical University

基　　金：陕西省科学技术研究发展计划基金资助项目(No.社发攻关2014K11-03-03-11)

摘　　要：目的:探讨柴胡疏肝散加味联合熊去氧胆酸治疗急性结石性胆囊炎患者的临床效果。方法:选取2013年8月至2014年7月延安大学咸阳医院收治的112例胆囊炎患者,将其随机分为研究组和对照组,每组56例。对照组采用熊去氧胆酸治疗,研究组采用柴胡疏肝散加味联合熊去氧胆酸治疗,比较患者的临床疗效、McGill疼痛量表评分。结果:治疗后,研究组的总有效率明显高于对照组(P<0.01),现有疼痛强度(PPI)、疼痛分级指数(PRI)及目测类比定级法(VAS)评分均明显低于对照组,且差异均具有统计学意义(均P<0.01)。结论:柴胡疏肝散加味联合熊去氧胆酸治疗急性结石性胆囊炎患者疗效确切,值得临床推广应用。Objective： To investigate the clinical effect of Chaihu shugan decoction combined with ursodeoxycholic acid on the treatment of cholecystitis. Methods： 112 cholecystitis patients from August 2013 to July 2014 in our hospital were selected and randomly divided into a research group and a control group, with 56 cases in each group. The patients in the control group received ursodeoxycholic acid, and those in the research group received Chaihu shugan decoction combined with ursodeoxycholic acid. The efficacy and the scores of McGill pain scale were compared between the two groups. Results： After treatment, the total response rate was higher, while present pain intensity （PPI）, pain rating index （PRI） and visual analogue scale （VAS） score were lower in the research group than those in the control group （ P d0.01）. Conclusion： Chaihu shugan decoction combined with ursodeoxycholie acid was effective in the treatment of eholecystitis, and was worthy of clinical application.

关 键 词：急性结石性胆囊炎 柴胡疏肝散加味 熊去氧胆酸 

分 类 号：R575.6[医药卫生—消化系统]