乳腺导管内癌的病理特征与超声造影的相关性  

Correlation between pathologic features and contrast-enhanced ultrasound in patients with breast ductal papilloma

作　　者：任静[1] 翁萍[1] 吐尔逊纳依[1] 耿玉荣[2] 胡佳俊[1] 刘娟[1] 

机构地区：[1]新疆医科大学第六附属医院超声科,乌鲁木齐市830002 [2]石河子大学医学院第一附属医院神经内科,832008

出　　处：《实用医学杂志》2017年第1期121-124,共4页The Journal of Practical Medicine

基　　金：新疆医科大学科研创新基金项目(编号:XJC2013218)

摘　　要：目的:探讨乳腺导管内癌的病理特征与超声造影的相关性。方法:2014年1月至2016年1月,选择在乳腺导管内肿块患者80例,其中乳腺导管内癌20例(导管内癌组),良性肿块患者60例(良性组),两组都进行常规超声、超声造影检查与病理特征分析。结果:相对于良性组,导管内癌组常规超声多表现为乳腺周边高回声、内部微钙化、边界缘毛刺和后方回声衰减(P<0.05)。导管内癌组的超声造影增强评分明显高于良性组(P<0.05)。在导管内癌组20例患者中,超声造影增强评分在不同淋巴结转移、分化类型、Dukes分期患者之间对比差异明显(P<0.05);Spearman等级相关系数分析也显示乳腺导管内癌的淋巴结转移、Dukes分期、分化类型等病理特征与超声造影也存在明显的相关性(r=0.341,0.368,-0.289,P<0.05)。结论:常规超声与超声造影诊断乳腺导管内癌能有很好的影像学特征,且超声造影增强情况与乳腺导管内癌的病理特征有明显相关性,能为乳腺导管内癌的早期诊断提供价值。Objective To investigate the correlation between pathologic features and contrast-enhanced ultrasound in patients with breast duetal papilloma. Methods From January 2014 to January 2016, 80 patients with breast intraduetal tumor treated in our hospital were selected, including 20 eases of breast duetal carcinoma （duetal carcinoma group） and 60 eases of benign tumor （benign group）. Both groups received conventional ultrasound, uhrasonie angiography, and pathological feature analysis. Results Breast surrounding hypereeho, internal micro calcification, border edge burr and posterior echo attenuation were more frequently seen oneonventional ultrasound in duetal carcinoma groupthan inbenign group （P 〈 0.05）. The average scores of contrast-enhanced ultrasound were significantly higher in duetal carcinoma group than in the control group （P 〈 0.05 ）. In the duetal carcinoma group, there were statistical significant differences betweenpatientswith different lymph node metastasis dukes staging, and differentiation types （P 〈 0.05）. Spearman rank correlation coefficient analysis showed that breast intraduetal carcinoma lymph node metastasis and dukes staging, differentiation types were markedly correlated with pathological features and ultrasound imaging （r = 0.341, 0.368, and -0.289; P 〈 0.05）. Conclusions Conventional ultrasound and contrast-enhanced ultrasound have very good imaging featuresin the diagnosis of breast intraduetal cancer, and there is correlation between pathologic features and contrast-enhanced ultrasound in patients with breast duetal papilloma, which can provide values for early diagnosis of breast duetal carcinoma.

关 键 词：超声造影 乳腺导管内乳头状瘤 病理特征 相关性 

分 类 号：R737.9[医药卫生—肿瘤]