超声引导下微波消融治疗甲状腺腺瘤的临床分析  

Clinical analysis of microwave ablation in the treatment of thyroid adenoma under ultrasound guidance

作　　者：栾洋[1] 刘绪舜[2] 王康磊[2] 王龙琦 徐奥博[2] 陈坚[2] 

机构地区：[1]南京中医药大学附属八一医院门诊部,210002 [2]南京中医药大学附属八一医院血管外科,南京210002

出　　处：《临床肿瘤学杂志》2016年第12期1103-1106,共4页Chinese Clinical Oncology

摘　　要：目的探讨超声引导下微波消融治疗甲状腺腺瘤的临床疗效和安全性。方法回顾性分析2014年7月至2016年7月74例行超声引导下微波消融治疗甲状腺腺瘤患者的临床资料,分析消融术后腺瘤体积缩小情况、术后甲状腺功能指标(三碘甲状腺原氨酸、甲状腺素、游离三碘甲状腺原氨酸、游离甲状腺素及促甲状腺激素)变化情况及术后并发症发生情况。结果 74例患者共微波消融结节104枚。所有患者术后恢复良好,仅1例术后出现轻微局部血肿,无其他并发症发生。术后随访无1例复发,术后1、3、6、12、24个月腺瘤体积缩小率分别为(11.73±37.21)%、(28.71±26.72)%、(53.33±38.24)%、(78.56±15.31)%和(94.28±4.54)%,术前与术后1个月甲状腺功能指标水平无显著性差异(P>0.05)。结论超声引导下微波消融治疗甲状腺腺瘤的安全性高、创伤小、术后恢复快,疗效确切而且美观,值得临床推广。Objective To explore the efficacy and safety of microwave ablation in the treatment of thyroid adenoma under ul- trasound guidance in clinic. Methods In this retrospective study, clinical data of 74 cases of thyroid adenoma undergoing ultrasound- guided microwave ablation were collected from July 2014 to July 2016. The volumetric reduction of adenoma and changes of thyroid function including triiodothyronine, thyroxine, free three iodine glycine, free thyroxine and thyroid-stimulating hormone as well as post- operative complications were analyzed. Results Under ultrasound guidance, 104 thyroid nodules were ablated by microwave. All pa- tients recovered well postoperatively and no complication occurred except for 1 case with mild local cervical hematoma. No thyroid ade- noma recurred in 74 cases. The loss of volume rates were （ 11.73±37.21）%, （28.71±26.72）%, （53.33±38. 24）%, （78.56± 15.31 ） % and （ 94. 28±4. 54） % at 1-, 3-, 6-, 12-and 24-month after operation, respectively. The postoperative changes in serum thy- roid-related hormone levels were not statistically significant when compared with the preoperative ones. Conclusion Ultrasound-guided microwave ablation was safe for thyroid adenoma with the advantages of less trauma and quick recovery. Moreover, it has satisfying cos- metic effect, worthy of clinical promotion.

关 键 词：甲状腺腺瘤 超声引导 微波消融 

分 类 号：R736.1[医药卫生—肿瘤]