纳米碳染色结合沿动脉血管走行分检右半结肠癌淋巴结  

Lymph nodes sorting based on nanometer carbon staining and supplying artery distribution in right-sided colon carcinoma

作　　者：赵玉洲[1] 韩广森[1] 陈小兵[1] 刘莺[1] 李剑[1] 顾焱晖[1] 马鹏飞[1] 刘晨宇[1] 霍明科 

机构地区：[1]河南省肿瘤医院普外科,郑州450008

出　　处：《中华普通外科杂志》2017年第1期12-14,共3页Chinese Journal of General Surgery

摘　　要：目的探讨纳米碳染色结合沿动脉血管走行分检右半结肠癌淋巴结的技术优势。方法选取2015年5月至2016年6月河南省肿瘤医院普外科5I例右半结肠癌患者，被随机分为纳米碳染色联合沿动脉血管分检组（观察组）24例和传统方法组（对照组）27例，比较两组检出淋巴结总数、平均检出淋巴结数、淋巴结〈12枚人数、阳性淋巴结数、淋巴结阳性率、患者转移率、平均直径〈5mm淋巴结数、平均直径〈5mm阳性淋巴结数、第一、二、三站淋巴结数和淋巴结分检时间。结果观察组检出淋巴结总数和阳性淋巴结总数均高于对照组（437比349、70比54）。两组淋巴结分检时间、检出的直径〈5min阳性淋巴结数目相比差异均有统计学意义[（13．1±3．2）min比（17．8±3．8）min，t=4．75，P=0．000；1．0±1．0比0．2±0．6，t=3．51，P=0．000]。两组检出淋巴结〈12枚人数、淋巴结阳性率和患者转移率相比差异均无统计学意义（均P〉0．05）。结论采用纳米碳染色联合沿动脉血管走行分检右半结肠癌淋巴结具有操作简便。获取淋巴结数目多，更有利于准确病理分期等优点。Objective To evaluate a novel lymph node （LN） sorting method on surgical resected sample guided by nanometer carbon staining and principle following the supplying artery tributory in rightsided colon carcinoma. Methods From May 2015 to June 2016, 51 patients were randomly divided into two groups adopting traditional LN sorting method and that of a combination of nanometer carbon and artery guided. The final LN status were compared between the 2 groups. Results The total LN number and the positive LN in novel method group were higher than control group （437 vs. 349,70 vs. 54 ）. The dissection time used, the number of harvested positive LN that was 〈 5 mm were significantly different [ （ 13.1 ± 3.2） min vs. （17.8±3.8）min,t=4.75,P=0.000; 1. 0 ±1. 0vs. 0.2±0.6,t=3.51,P=0.000]. The number of patients with harvested LN less than 12, the rate of positive lymph nodes, the rate of metastasis were not significantly different （ all P 〉 0. 05 ） between the two groups. Conclusions Use of nanometer carbon development combined with artery approach faeilitates LN sorting, yielding more positive LNs, and increating the accuracy of pathological staging in right-sided colon cancer.

关 键 词：结肠肿瘤 淋巴结 纳米碳 

分 类 号：R735.35[医药卫生—肿瘤]