口腔正畸治疗对口腔中细菌微生态的影响  

Effects of orthodontic treatment on bacterial microecology in oral cavity

作　　者：周佳卉[1] 

机构地区：[1]广东省珠海市人民医院口腔科,珠海519000

出　　处：《上海医药》2017年第1期44-46,75,共4页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的 :探究口腔正畸治疗患者口腔中细菌微生态的变化情况。方法 :抽取进行口腔正畸治疗的45例患者作为观察组,45例口腔健康群体作为对照组,取所有患者牙龈沟内液体予以细菌培养并进行对比分析。结果 :正畸前,观察组牙龈沟细菌的分布情况、情况与对照组相比无显著差异,细菌类型主要是球菌与杆菌;正畸后1个月、3个月,观察组的球菌、杆菌所占比例减少,而螺旋体、梭状菌所占比例增加(P<0.05);观察组核梭杆菌、卟啉单胞菌、伴放线放线杆菌、福塞氏类杆菌等口腔细菌的检出率以及碱性磷酸酶(ALP)活性显著高于对照组(P<0.05)。结论 :口腔正畸能够改变口腔细菌微生态,提高ALP的水平以及活性,增加核梭杆菌、卟啉单胞菌、伴放线放线杆菌、福塞氏类杆菌的检出率,进而引起炎症反应。Objective： To investigate the changes of bacterial microecology in oral cavity of patients undergoing orthodontic treatment. Methods： Forty-five cases of patients undergoing orthodontic treatment were selected as an observation group and 45 cases of orally healthy volunteers were selected as a control group. The bacterial cultures from gingival sulcus fluid of all patients were compared and analyzed. Results： Before orthodontic treatment, the distribution of gingival crevicular bacteria in the observation group showed no significant differences compared with that in the control group, and bacterial types were mainly cocci and bacilli. The proportion of cocci and bacilli in the observation group decreased, while the proportion of spirochete and fusiforms increased at a month and three months after treatment（P〈0.05）. The detection rate of oral bacteria including Fusobacterium nucleatum, Porphyromonas, Actinobacillus actinomycetem comitans and Bacteroides forsythus, and alkaline phosphatase（ALP） activity were significantly higher in the observation group than in the control group（P〈0.05）. Conclusion： Orthodontic treatment can change the oral microflora, and increase the level and activity of ALP as well as the detection rate of Fusobacterium gingivalis, Porphyromonas and Actinobacillus actinomycetem comitans, and Bacteroides forsythus, which can cause inflammation.

关 键 词：口腔正畸 细菌微生态 ALP活性 

分 类 号：R783.5[医药卫生—口腔医学]