中药复方辨证治疗老年性痴呆的临床和实验进展  

Experimental and Clinical Study Progress in Differentiation and Treatment of Senile Dementia using Traditional Chinese Compound Prescription

作　　者：张立敏[1] 安红梅[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032

出　　处：《中华中医药学刊》2017年第1期124-126,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81470195);上海市卫生和计划生育委员会中医药科研基金项目(2014XZ005A);上海市中医药事业发展三年行动计划项目(ZY3-JSFC-2-2003)

摘　　要：老年性痴呆又称阿尔茨海默病,是发生于老年和老年前期、以进行性认知功能障碍和行为损害为特征的中枢神经系统退行性病变。临床上通过辨证论治运用相应的复方,并采用随机对照等研究方法观察疗效,证实了中药复方治疗老年性痴呆的有效性。实验中使用可重复的动物模型,研究中药复方的作用机制,为中医药治疗老年性痴呆提供了依据。从临床治疗和实验研究两方面,归纳总结了中药复方治疗老年性痴呆的进展,以期为临床治疗提供参考。Alzheimer＇s disease, also named as senile dementia, is a kind of central nervous system degenerative dis- ease characterized by progressive cognitive dysfunction and behavioral impairment which occurs in pre - elderly and elderly periods. The effectiveness of Traditional Chinese Compound Prescription in treating senile dementia has been confirmed by randomized controlled trials（RCTs）. The RCTs built up the basis for the traditional Chinese medicine（TCM） treatment of senile dementia through mechanism research by using reused animal models. The purpose of this article is to summarize the development of TCM treatment of senile dementia regarding to clinical treatment and experimental study and thus provide the reference for future treatment.

关 键 词：老年性痴呆 中药复方 临床治疗 实验研究 

分 类 号：R749.16[医药卫生—神经病学与精神病学]