沈阳市1490名0～6岁体检儿童血清维生素A水平现状分析  

Analysis of the present situation of serum vitamin A level in 1 490 children aged from 0 to 6 years old in Shenyang

作　　者：廖新[1] 穆亚平[2] 李玢[2] 文江舸[1] 李娜[1] 

机构地区：[1]沈阳市儿童医院儿童保健科,沈阳110032 [2]沈阳市儿童医院儿内科,沈阳110032

出　　处：《中国中西医结合儿科学》2016年第5期522-524,共3页Chinese Pediatrics of Integrated Traditional and Western Medicine

摘　　要：目的了解沈阳市0~6岁体检儿童维生素A（VitA）水平现状。方法以2015年2月至2016年2月在沈阳市儿童医院儿保门诊健康体检的0~6岁儿童为研究对象,按年龄分为0~1岁组、〉1~3岁组、〉3~6岁组,共1 490名,采用高效液相色谱法检测血清VitA水平。结果 0~6岁体检儿童血清VitA平均水平为（1.10±0.26）μmol/L,亚临床维生素A缺乏（SVAD）发生率是4.0%,可疑SVAD发生率是36.6%。0~1岁组儿童血清VitA水平低于〉1~3岁组和〉3~6岁组儿童,差异有统计学意义（P〈0.05）。〉1~3岁组和〉3~6岁组儿童血清VitA水平差异无统计学意义（P〉0.05）。各年龄组间SVAD和可疑SVAD发生率比较,差异无统计学意义（P〉0.05）。1个月内患腹泻、呼吸系统感染患儿SVAD发生率高于健康儿童（P〈0.01）。结论目前沈阳市学龄前儿童无临床表现的SVAD及可疑SVAD的发病率仍较高,应提高全社会对VitA的认识,积极预防和干预这一年龄阶段儿童尤其是婴幼儿维生素A缺乏症的发生,从而减少呼吸系统和消化系统疾病的发生。Objective To know about the children vitamin A （VA） level from 0 to 6 years old in Shenyang . Methods From February 2015 to February 2016 ,the children aged 0 to 6 were selected as the study subjects. The children were divided into 0 to1 age group,〉1 to 3 age group,〉3 to 6 age group,a total of 1 490,the use of high performance liquid chromatography to detect serum VitA levels. Results The mean serum VitA level was （1.10 ± 0.26）μmol/L, the incidence of subclinical vitamin A deficiency was 4.0%, and the incidence of suspicious SVAD was 36.6 %. The serum VitA level of 0 to 1-year-old children was significantly lower than that of 〉1 to 3-year-old children and 〉3 to 6-year-old ehildren（P〈0.05）. There was no significant difference in serum VitA between 〉 1 to 3-year-old and 〉 3 to 6-year-old children（P〉 0.05）. There was no significant difference in the incidence of SVAD and suspicious SVAD among all age groups （P〉 0. 05）. The incidence of SVAD in children with diarrhea and respiratory infection was higher than that in healthy children within one month（P〈0. 01）. Conclusion The prevalence of SVAD and suspicious SVAD in preschool children in our city is still relatively high. It is necessary to raise the awareness of VitA in preschool children and to prevent and intervene the occurrence of vitamin A deficiency in children,especially infants and young children. Thereby fundamentally helping reduce the incidence of respiratory and digestive diseases.

关 键 词：维生素A缺乏 亚临床维生素A缺乏 儿童 

分 类 号：R153.2[医药卫生—营养与食品卫生学]