维医沙疗下股动脉双向流固耦合脉动血流动力学研究  

The effects of sand treatment in Uyghur medicine on the pulsatile hemodynamics of femoral artery bidirectional fluid-solid coupling

作　　者：布热比.依明 富荣昌[1] 阿达依.谢尔亚孜旦 迪丽娜尔.马合木提 YIMING-Bureb i FU Rong-chang XIEERYA ZIDA N.A dayi MA HEMUTI.(Dilinaer. School of Mechanical Engineering, Xinjiang University, the Xinjiang Uyghur Autonomous Region, Urumqi 830047, Chin)

机构地区：[1]新疆大学机械工程学院,乌鲁木齐830047

出　　处：《介入放射学杂志》2017年第1期49-54,共6页Journal of Interventional Radiology

基　　金：国家自然科学基金(31460245;81160458);新疆维吾尔自治区自然科学基金(2014211A005)

摘　　要：目的研究流固耦合作用下室内维医沙疗对人体股动脉血流动力学的影响,探讨维医沙疗对动脉粥样硬化成因的作用机制及对血管破裂的影响。方法在室内维医沙疗实验中对年轻健康受试者进行维医沙疗研究,对受试者心率、股动脉血流速度峰值及内径作统计学分析;重构人体股动脉三维流固耦合模型,将正弦函数作为初始条件,用Fluent软件分别对沙疗前后血液流动作非定场双向流固耦合模拟,分析维医沙疗对股动脉壁面切应力及von Mises等效应力的影响。结果维医沙疗前后受试者心率平均值分别为(76.32±11.40)次/min、(92.69±16.09)次/min,差异有统计学意义(P<0.05);沙疗前后股动脉血流雷诺数分别为1855.35、2518.43;沙疗对股动脉壁面切应力及von Mises等效应力增高的影响较为明显。结论维医沙疗可增大股动脉血流雷诺数,改善人体股动脉血液流动状态,但沙疗后股动脉血流方式由层流变为紊流,很可能会导致血管瘤,因此对血管内壁较薄弱人群要控制埋沙时间、埋沙厚度及温度。维医沙疗可增高壁面切应力,对预防动脉壁增厚引起的动脉粥样硬化及血栓形成有一定的积极作用。维医沙疗后von Mises等效应力明显增加可加大股动脉在分叉部分破裂可能,沙疗时需谨慎。Objective To investigate the effects of Uyghur indoor sand therapy on the hemodynamics of femoral artery bidirectional fluid-solid coupling, and to discuss the influence of Uyghur indoor sand therapy on the formation of atherosclerosis as well as on the rupture of blood vessels. Methods This study of indoor Uyghur sand therapy was conducted in young healthy volunteers. The heart rate, peak value of femoral artery blood flow velocity and inner diameter were determined, and the resuhs were statistically analyzed. Three dimensional fluid-solid coupling model of human femoral artery was reconstructed. Taking the sine function as the initial condition, the non-steady field bidirectional fluid-solid coupling simulation was conducted by using Fluent software, and the effect of indoor Uyghur sand therapy on femoral artery wall shear stress as well as on yon Mises equivalent stress was evaluated. Results The average heart rates before and after indoor Uyghur sand therapy were （76.32＋11.40） beats per minute and （92.69＋16.09） beats per minute respectively, the difference was statistically significant （P〈0.05）. The Renolds number of femoral artery before and after indoor Uyghur sand therapy was 1855.35 and 2518.4 respectively. The Uyghur sand therapy had more obvious influence on the increase of femoral artery wall shear stress and yon Mises equivalent stress. Conclusion Uyghur sand therapy can increase Renolds number of femoral artery and improve the blood flow state of human femoral artery, but after the treatment the femoral artery blood flow pattern changed from laminar flow to turbulence flow, which may lead to the formation of hemangioma, therefore, for patients whose inner wall of blood vessel are thinner the sand-buried time, burying-sand thickness and temperature should be strictly controlled. Uyghur sand therapy can also increase wall shear stress, which plays a certain positive role in preventing atherosclerosis and thrombosis caused by thickening of the arterial wall. After Uyghur sand therapy,

关 键 词：维医沙疗 血流动力学 计算流体动力学 用户自定义函数 Fluent双向流-固耦合 脉动流 壁面切应力 血管破裂 

分 类 号：R29[医药卫生—民族医学]