胃肠道间质瘤患者应用外科治疗的临床资料回顾性分析  

Retrospective Analysis of 81 Cases of Gastrointestinal Stromal Tumors

作　　者：孙春磊[1] 滕安宝[1] 姚寒晖[1] 朱志强[1] SUN Chun-lei TENG An-bao YAO Han-hui ZHU Zhi-qiang(Department of General Surgery, Anhui Provincial Hospital, Hefei 230001, Anhui , China)

机构地区：[1]安徽省立医院普外科,合肥230001

出　　处：《中国现代手术学杂志》2016年第5期331-334,共4页Chinese Journal of Modern Operative Surgery

摘　　要：目的回顾性分析胃肠道间质瘤患者应用外科治疗的临床特点、诊治方法及预后效果。方法回顾性分析2010年1月至2013年1月间安徽省立医院胃肠外科收治的手术治疗的81例胃肠道间质瘤患者的临床资料,观察分析患者的诊治效果、术后生存情况,并对其预后情况进行单因素及多因素回归分析。结果所有81例患者的恶性危险度分级显示,41例为高度危险,24例为中度危险,10例为低度危险,6例为极低危险,单因素分析发现患者短期预后(术后3年生存率)与其肿瘤大小、性质、核分裂相及复发转移明显相关;在多因素Cox回归分析中,患者的3年生存率与肿瘤大小、性质及复发转移呈明显正相关。结论对可切除的胃肠道间质瘤患者应进行外科完全切除,可切除的患者的预后与肿瘤大小、危险度及复发转移有关。Objective To analyze the clinical characteristics,diagnosis and treatment methods and the prognosis of gastrointestinal stromal tumor patients. Methods A total of 81 patients were studied who were present in our hospital from January 2013 to January 2016 with localized primary GIST and underwent surgical resection. The clinical information and the prognostic influencing factors were retrospectively analyzed.Results There were 41 cases of high risk,24 cases of moderate risk,10 cases of low risk and 6 cases of extreme low risk according to the National Institutes of Health（ NIH） consensus classification system. The influencing factors of the 3-year survival rate were tumor size,consensus classification,mitotic count,recurrence and metastasis. But the multivariate Cox regression analysis showed that tumor size,consensus classification and recurrence and metastasis were significantly positively correlated with the survival rate.Conclusion The complete resection of gastrointestinal stromal tumor as far as possible is the first choice of clinical treatment. The tumor size,consensus classification and recurrence and metastasis are relevant to the prognosis of patients.

关 键 词：胃肠道间质瘤 外科手术 

分 类 号：R735[医药卫生—肿瘤]