不同病因肝硬化患者血清肝纤维化指标结果分析  

Analysis of serum liver fibrosis indexes in cirrhosis patients with different etiology

作　　者：任丽楠[1] 祁兴顺[1] 陈江[1] 郭晓钟[1] 

机构地区：[1]沈阳军区总医院消化内科,辽宁沈阳110840

出　　处：《胃肠病学和肝病学杂志》2017年第1期23-24,共2页Chinese Journal of Gastroenterology and Hepatology

基　　金：国家自然科学基金资助项目(81500474);辽宁省博士科研启动基金(20111094);辽宁省自然科学基金(201602787)

摘　　要：目的探讨不同病因肝硬化患者血清肝纤维化指标的变化特点。方法收集2013年1月-2014年4月沈阳军区总医院确诊为肝硬化患者198例,并按病因分为5组,检测其血清肝纤维化指标水平。结果 (1)酒精性肝硬化组以LN、Ⅳ-C升高为主;(2)药物性肝硬化组以HA升高为主;(3)肝炎后肝硬化组以PC-Ⅲ升高为主。酒精性肝硬化组与其他组各指标比较差异有统计学意义(P<0.05)。结论血清肝纤维化指标对肝硬化的预防和治疗有重要临床意义。Objective To investigate the change of serum liver fibrosis indexes in patients with cirrhosis. Methods All of 198 cirrhosis patients with different etiology from Jan. 2013 to Apr. 2014 in the General Hospital of Shenyang Military were collected,and divided into 5 groups according to the etiology. Results（1） LN,Ⅳ-C were increased in alcoholic cirrhosis group.（2） HA was increased in drug cirrhosis group.（3） PC-Ⅲ was increased in posthepatitic cirrhosis group. There were significant differences in all liver fibrosis between alcoholic cirrhosis group and other groups（P〈0. 05）. Conclusion The serum liver fibrosis indexes are important for prevention and treatment of cirrhosis.

关 键 词：肝硬化 肝纤维化 病因 

分 类 号：R575.2[医药卫生—消化系统]