不同入路显微外科手术治疗脑胶质瘤的疗效观察  

Efficacy of different microsurgical routes of entry in the treatment of glioma

作　　者：张文燕[1] 王翠英[2] 赵宝帅 崔静 景岳 

机构地区：[1]河北省衡水市第四人民医院神经外科,衡水053000 [2]河北省衡水市第四人民医院肿瘤科,衡水053000 [3]哈励孙国际和平医院神经外科,衡水053000 [4]哈励孙国际和平医院耳鼻喉科,衡水053000

出　　处：《中国肿瘤临床与康复》2016年第12期1471-1473,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的探讨不同入路显微外科手术治疗脑胶质瘤的临床疗效及对生活质量的影响。方法选取2012年9月至2015年9月间河北省衡水市第四人民医院收治的脑胶质瘤患者80例,根据肿瘤部位选择不同的显微外科手术入路,术后随访12个月,评估患者手术前后临床症状改善情况、生活质量评分及术后不良反应。结果与术前相比,患者术后临床症状基本消失,差异有统计学意义(P<0.05)。术后生活质量评分显著高于术前,差异有统计学意义(P<0.05)。术后随访过程中仅2例出现感染,处理后治愈。结论根据脑胶质瘤部位选择不同的入路行显微外科手术治疗脑胶质瘤,可提高临床疗效,改善生活质量,减少不良反应。Objective To investigate the efficacy of different microsurgical routes of entry in the treatment of glioma and effect on quality of life. Methods Select 80 patients with glioma treated at Hengshui Fourth People’s Hospital from September 2012 to September 2015. Patients received different operative routes of entry according to the location of tumors. Patients were followed for 12 months after the surgery,and pre-and post-operative symptoms,quality of life and adverse reactions were evaluated. Results Symptoms almost resolved after surgery（ P 〈 0. 05）. Score of life quality after surgery was higher than that before surgery（ P 〈 0. 05）. Only 2 patients got infected after surgery,and they were soon cured. Conclusion To choose different microsurgical routes of entry based on the site of the tumor lesions can effectively improve the clinical efficacy improve quality of life and reduce adverse reactions in patients with glioma.

关 键 词：显微外科 手术入路 脑胶质瘤 生活质量 

分 类 号：R739.41[医药卫生—肿瘤]