甲硝唑联合乙酰螺旋霉素与牙周宁治疗成年人牙周炎的临床治疗效果比较  

Comparison of the Clinical Effects for Metronidazole Combined Acetylspiramycin and Rice Bran Sterol Tablets in the Treatment of Adult Periodontitis

作　　者：王珺 欧龙[2] 罗芸[3] 杨婷[2] 谢潇[4] WANG Jun OU Long LUO Yun YANG Ting XIE Xiao(Department of Stomatology, Naval Authority Clinics, Beijing, 100036, China Department of Periodontal Membrane, General Hospital of PLA, Beijing, 100841, China Laboratory of Cell Biology, Institute of Geriatric Research, General Hospital of PLA, Beijing, 100853, China Department of Stomatology, Air Force Clinic of PLA, Beijing, 100841, China)

机构地区：[1]海军机关门诊部口腔科,北京100036 [2]解放军总医院牙周黏膜科,北京100841 [3]解放军总医院老年病医学研究所细胞生物研究室,北京100853 [4]解放军空军门诊部口腔科,北京100841

出　　处：《现代生物医学进展》2016年第35期6862-6865,共4页Progress in Modern Biomedicine

基　　金：北京市科技计划首都人群健康培育专项课题(Z131100004013091)

摘　　要：目的:探讨临床有效治疗成年人牙周炎的可靠方法,从而为成年人牙周炎的相关研究和临床实践提供指导帮助。方法:选取我院2012年12月至2014年11月期间临床收治的成年人牙周炎患者108例为研究对象,根据患者临床治疗方法的不同,将其分成了研究组(给予甲硝唑联合乙酰螺旋霉素治疗)和对照组(给予牙周宁治疗),对其临床治疗效果进行了比较研究。结果:研究组患者的牙龈指数、菌斑指数和牙周袋深度等三项指标均明显低于对照组患者指标水平,且差异有统计学意义;总有效率组间比较,研究组高于对照组,且差异有统计学意义;总不良反应发生率组间比较,研究组低于对照组,且差异有统计学意义。结论:采用甲硝唑联合乙酰螺旋霉素治疗成年人牙周炎的临床治疗效果显著是临床治疗成年人牙周炎的理想方式。Objective： To explore the effective and reliable method for clinical treatment of adult periodontitis, so as to provide guidance and assistance for research and clinical practice of adult periodontitis. Methods： 108 cases of adult periodontitis in our hospital from December 2012 to October 2014 were chosen as the research objects. According to the differences of the clinical treatment methods, they were divided into the study group （metronidazole combined acetylspiramycin） and the control group （rice bran sterol tablets）. The clinical effects were taken for comparative study. Results： The gingival index, plaque index and periodontal pocket depth three indicators of the study group were significantly lower than the levels of the control group, and the differences were with statistical significance. The total efficiency rates compared between the two groups, the study group was higher than the control group, and the differences were with statistical significance. The total incidence of adverse reactions compared between the two groups, the study group was lower than the control group, and the differences were with statistical significance. Conclusion： The clinical effect of the application of metronidazole combined acetylspiramycin in the treatment of adult periodontitis is significant, and it is an ideal way in clinical treatment of adult periodontitis.

关 键 词：甲硝唑 乙酰螺旋霉素 牙周宁 成年人牙周炎 

分 类 号：R781.4[医药卫生—口腔医学]