不同介入治疗模式对晚期肝癌患者的疗效分析  

The analysis of effect of different interventional modes in treating 186 patients with hepatocellular carcinoma

作　　者：卓德强[1] 徐志宏 汪明月[1] 鲁植艳[1] ZHUO Deqiang XU Zhihong WANG Mingyue et al(Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China)

机构地区：[1]武汉大学中南医院影像科,430071 [2]湖北省团风县人民医院放射科

出　　处：《临床外科杂志》2016年第12期937-939,共3页Journal of Clinical Surgery

摘　　要：目的评价不同介入治疗模式治疗晚期肝癌的临床疗效。方法不能手术治疗的晚期肝癌患者186例，将186例患者分成3组。A组62例，采取肝动脉栓塞化疗（TACE）；B组60例，采取射频消融（RFA）治疗；C组64例，采取TACE联合RFA治疗，比较三组患者介入治疗效果。结果C组患者肿瘤完全反应率、血清甲胎蛋白（AFP）变化以及介入治疗后1、3年存活率明显高于A、B组，差异有统计学意义（P〈0．05）；A、B组间比较差异无统计学意义（P〉0．05）。结论TACE联合RFA治疗肝癌，疗效显著，可提高患者短期生存率。Objective Evaluate the effect of different interventional therapy in treatment of advanced liver cancer patients. Methods 186 patients with hepatocellular carcinoma were retrospectively analyzed. 62 patients were treated with transhepatic arterial chemotherapy and embolization （TACE） （group A） ,60 patients were treated with radio frequency ablation（RFA） （group B）and 64 patients were treated with TACE combined with RFA （group C）. Recored completed tumor response rate, AFP level and 1,3 year-survival rate among the three groups. Results Compared with group A and B, the completed tumor response rate, AFP level and 1,3 year-survival rate were higher in group C （P 〈 0.05 ）. However, there was no statistical significant difference between group A and B （ P 〉 0.05 ）. Conclusion TACE combined with RFA can improve the short-term survival rate,is an ideal way to treat hepatocellular carcinoma.

关 键 词：肝癌 介入治疗 射频消融 生存率 

分 类 号：R735.7[医药卫生—肿瘤]