2004—2013年铁强化酱油对我国贫血预防控制作用的评估  

Evaluation of iron fortified soy sauce on changes of anemia prevalence in 2004-2013

作　　者：魏艳丽[1] 霍军生[1] 殷继永[1] 孙静[1] 黄建[1] WEI Yanli HUO Junsheng YIN Jiyong SUN Jing HUANG Jian(National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China)

机构地区：[1]中国疾病预防控制中心营养与健康所,北京100050

出　　处：《卫生研究》2017年第1期136-142,共7页Journal of Hygiene Research

基　　金：全球营养改善联盟资助项目

摘　　要：目的分析2004—2013年铁强化酱油(铁酱油,IFSS)项目对中国人群贫血发生率持续下降的作用,了解铁酱油项目对贫血的预防和控制作用。方法通过对已报道的铁酱油随机双盲对照干预试验进行Meta分析,确定铁酱油对贫血的作用。根据铁酱油产量及消费人群数据并结合2002年全国营养调查和2015年中国居民营养与慢病状况数据进行分析。通过确定铁酱油消费人群贫血率变化,来推断铁酱油对贫血发生率下降的归因。结果 Meta分析结果显示,食用IFSS人群的贫血率约为不食用IFSS人群贫血率的27%。铁酱油10年间达到有效覆盖时间的覆盖人数为1.86亿,其中2849万人贫血通过铁酱油得到改善。采用铁酱油每改善一名贫血患者的成本为0.12元。结论铁酱油项目对居民贫血发生率持续下降有一定作用,归因占到23.2%,但仍存在不确定因素,可导致分析结果的偏差。Objective To understand the role of iron fortified soy sauce（ IFSS） on the decrease of anemia prevalence in Chinese population in 2004- 2013. Methods Meta analysis was used to analyze the effect of IFSS on anemia through published randomcontrol studies on the population intervention with IFSS. Integrated with other data from IFSS statistic on IFSS production and consumption,the recovered population from IFSS was identified and anemia decrease determined,therefore,IFSS contribution to anemia change could be estimated. Results By Meta analysis,the anemia rate of the population consumed IFSS was 27% compared with the anemia rate of the population non-consumed IFSS. In the past 10 years,IFSS had covered more than 186 millions population with effect validity time. A total of 28. 49 millions anemic population recovered from anemia.To recover one anemic with IFSS,the cost was 0. 12 RMB. Conclusion IFSS has showed effect on the decline of anemia prevalence in last decade,23. 2% of the decrease was estimated owe to IFSS project,but there are unidentified factors which may bring bias to the result.

关 键 词：贫血 铁酱油 META分析 营养干预 

分 类 号：R556.3[医药卫生—血液循环系统疾病] TS264.21[医药卫生—内科学]