子野权重优化应用于宫颈癌根治术后调强放疗计划中的分析  

The Analysis of Segment Weight Optimization on IMRT Plan Applied to Patients with Postoperative Cervical Cancer

作　　者：吴煜良[1] 何松美[1] 张纯[1] 吴伟艺[1] 莫杰明[1] WU Yu-liang HE Song-mei ZHANG Chun WU Wei-yi MO Jie-ming(The Department of Radiation Ontology, Dongguan People＇s Hospital, Dongguan52305)

机构地区：[1]广东省东莞市人民医院,东莞523059

出　　处：《实用中西医结合临床》2016年第10期7-8,共2页Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine

基　　金：广东省东莞市医疗卫生科技计划项目(编号:20131051010111)

摘　　要：目的：探究子野权重（SWO）优化应用于宫颈癌根治术后调强放疗计划中的效果。方法：对2014年4月~2016年3月在我院进行宫颈癌根治手术的患者在根治术后进行了静态调强方式优化调强放疗计划（S-IMRT）和子野权重优化调强放疗计划（SWO-IMRT）,比较两种计划的总子野数、总机器跳数（MU）、均匀性指数（HI）、适形度指数（CI）以及周围危及器官的受照剂量。结果：SWO-IMRT计划的总子野数和总MU明显低于S-IMRT计划,差异具有显著性（P〈0.05）;S-IMRT和SWO-IMRT两种调强放疗计划的HI和CI比较无显著差异（P〉0.05）;SWO-IMRT计划中直肠、小肠以及膀胱的受照射剂量明显低于S-IMRT计划,差异具有显著性（P〈0.05）。结论：宫颈癌根治术后使用子野权重优化调强放疗计划后能有效的减少正常组织的照射剂量,缩短了治疗时间。Objective： To study the effect of segment weight optimization （SWO） on Intensity-modulated radiation therapy （IMRT） applied to patients with of postoperative cervical cancer. Methods： From April 2014 to March 2016,20 cases with cervical cancer surgery were chosen as research subjects to receive static IMRT Optimization IMRT plan （S-IMRT） and the SWO-IMRT plan （SWO-IMRT）, respectivey. The total number of segments, the total monitor unit（MU）, homogeneity index （HI）, conformal index （CI） and radiation dose of surrounding organs at risk were compared between two groups. Results： The total number of segments and total MU for SWO-IMRT plan were significantly lower than those for the S-IMRT plan, the difference was significant （P〈0.05）; HI and CI for SWO-IMRT and S-IMRT were not significant （P〉0.05）. Conclusion： Segment weight optimization on IMRT plan applied to patients with postoperative cervical cancer can effectively reduce post-dose to normal tissue and shorten the treatment time.

关 键 词：子野权重优化 宫颈癌根治术 调强放疗计划 

分 类 号：R737.33[医药卫生—肿瘤]