北京市丰台社区脑卒中高危人群颈动脉筛查结果分析  

Analysis of the investigation of carotid atherosclerosis in high-risk population of stroke in Beijing Fengtai community

作　　者：张丽[1] 张志辰[1] 谢淑芸[2] 梁晓[3] 张允岭[4] ZHANG Li ZHANG Zhi-chen XIE Shu-yun LIANG Xiao ZHANG Yun-ling(The Second Department of Encephalopathy, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China Department of Cardiology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078 Beijing University of Chinese Medicine, Beijing 100029 Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078)

机构地区：[1]北京中医药大学东方医院脑病二科,北京100078 [2]北京中医药大学东方医院心内科,北京100078 [3]北京中医药大学,北京100029 [4]北京中医药大学东方医院,北京100078

出　　处：《北京中医药》2016年第12期1121-1124,共4页Beijing Journal of Traditional Chinese Medicine

基　　金：2016年北京中医药大学自主选题(2016-JYB-JSMS-051);北京中医药大学研究创新团队项目(2011-CXTD-23);2011年北京市科技计划项目(Z111107056811040);2011年医改重大专项"国家脑卒中高危人群筛查与干预试点项目"

摘　　要：目的探讨影响脑卒中高危人群颈动脉硬化及斑块形成的相关危险因素。方法对3215例脑卒中高危人群进行颈动脉B超筛查,根据内膜是否增厚及斑块数量进行分组,比较各组内膜是否增厚、斑块数量与高危因素间的相互关系。结果脑卒中高危人群中有内膜增厚组与无内膜增厚组在性别、血脂异常、糖尿病病史方面差异有统计学意义(P<0.05);斑块数量不同组人群在性别、吸烟与否、超重、卒中家族史差异有统计学意义(P<0.05);多因素Logistic回归分析显示,颈动脉内膜增厚与否与血脂异常、糖尿病明显相关;内膜增厚与否在虚证患者中差异有统计学意义(P<0.05)。结论血脂异常、糖尿病可能是颈动脉内膜增厚的独立危险因素;斑块形成的多少受吸烟、超重、卒中家族史影响更明显。在有颈动脉内膜增厚患者中虚证较实证更多见。Objective To investigate the correlation of carotid artery plaque and other risk factors in high-risk stroke population. Methods 3215 cases of high-risk population of stroke were investigated by carotid artery ultrasound and then divided into the different groups by carotid intima-media thickening,the number of plaque,and then the interrelations of risk factors among the groups were compared. Results There were significantly statistical differences in gender,dyslipidemia,and diabetes history between the intimal thickening group and non intimal thickening group in high-risk stroke population（ P 〈 0. 05）. There were significantly statistical differences in the number of plaques between the different groups in the sex,smoking or not,overweight,family history of stroke（ P〈 0. 05）. Logistic multi factor regression analysis showed that dyslipidemia and diabetes mellitus were associated with intima media thickness（ IMT） of carotid artery. There was statistical significance in patients with deficiency syndrome in difference of intimal thickening（ P〈 0. 05）. Conclusion Dyslipidemia and diabetes may be the independent risk factors for carotid intimal thickening,and the formation of plaque is more significantly influenced by smoking,overweight,and family history of stroke. In patients with carotid artery intimal thickening,deficiency syndrome is more seen than the excess syndrome.

关 键 词：脑卒中 颈动脉粥样硬化 高危人群 中医证候 相关性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]