上皮性卵巢癌侵袭转移机制相关microRNA的研究进展  

Research Advances of MicroRNA in Invasion and Metastasis Mechanism of Epithelial Ovarian Cancer

作　　者：彭靓[1] 叶萍[1] 谢晓英[2] 朱亚飞[2] 

机构地区：[1]赣南医学院,江西赣州341000 [2]赣南医学院第一附属医院妇产科,江西赣州341000

出　　处：《赣南医学院学报》2016年第6期989-992,共4页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：microRNA是一类进化上保守的非编码小分子RNA,其具有参与转录后基因表达调控的功能,与肿瘤发生发展、诊断、治疗等多个环节密切相关,是近年来研究热点。在所有妇科恶性肿瘤中,上皮性卵巢癌(Epithelial ovarian cancer,EOC)是导致女性死亡的主要原因,对妇女生命造成严重威胁。本文就上皮性卵巢癌侵袭转移机制相关microRNA的研究进展做一综述。MicroRNA is a kind of evolutionary conserved non encoding small molecule RNA,which has the function in the post transcriptional regulation of gene expression. It closely relates with tumor development,diagnosis,treatment and other aspects. It is the hot spot of research in recent years. In all gynecological malignant tumors,epithelial ovarian cancer accounts for a major cause of death,which causes serious threat to women＇s lives. In this paper,the research progress of microRNA in epithelial ovarian cancer invasion and metastasis is reviewed.

关 键 词：MICRORNA 上皮性卵巢癌 转移 侵袭 

分 类 号：R730.231[医药卫生—肿瘤]