CT透视引导下经皮肺穿刺活检对肺部磨玻璃样病变诊断价值的Meta分析  

Diagnostic Accuracy of Percutaneous Lung Biopsy Under CT Fluoroscopy Guidance for Ground-Glass Opacity Pulmonary Lesions: a Meta-Analysis

作　　者：王小铭 黄显龙 WANG Xiaoming HUANG Xianlong.(Department of Radiology, Chongqing People＇ s Hospital, Chongqing 400014, P. R. China)

机构地区：[1]重庆市人民医院放射科,400014

出　　处：《临床放射学杂志》2017年第1期123-127,共5页Journal of Clinical Radiology

摘　　要：目的应用Meta分析方法探讨CT透视(CTF)引导下经皮肺穿刺活检(PTNB)对肺部磨玻璃样病变(GGO)的诊断价值。方法系统检索PUBMED、EMBASE、EBSCO、OVID外文数据库以及CNKI、CBM、VIP和万方中文数据库,查找所有关于CTF引导下PTNB诊断肺部GGO的相关文献。数据分析采用Meta-Disc 1.4和Stata12.0软件进行。结果纳入研究4篇(n=246)。汇总灵敏度、特异度、阳性似然比(+LR)、阴性似然比(-LR)、诊断比值比(DOR)及95%可信区间(95%CI)分别为0.91(0.86~0.95)、1.00(0.91~1.00)、18.64(4.83~71.93)、0.11(0.05~0.26)、153.17(30.78~762.33)。汇总受试者工作特性曲线(SROC)并计算曲线下面积(AUC)为0.98。结论对于肺部GGO的诊断,CTF引导下PTNB具有较高的灵敏度、特异度和准确率,可作为肺部的GGO重要临床诊断方法之一。Objective A Meta-analysis To evaluate the value of CT fluoroscopy（ CTF） guided percutaneous transthoracic needle biopsy（ PTNB） for the diagnosis of lung ground-glass opacity（ GGO）. Methods Relevant English and Chinese language studies were searched on the PUBMED,EMBASE,EBSCO,OVID,CNKI,CBM,VIP,and WANFANG database,respectively. Data were calculated with software of Meta-Disc 1. 4 and Stata12. 0. Results 4 4 of 82 retrieved studies were included,the pooled sensitivity,specificity,＋ LR,– LR,and DOR with 95% confidence interval were 0. 91（ 0. 86- 0. 95）,1. 00（ 0. 91- 1. 00）,18. 64（ 4. 83- 71. 93）,0. 11（ 0. 05- 0. 26） and 153. 17（ 30. 78- 762. 33）,respectively. The area under the curve（ AUC） of the summary receiver operating characteristic（ SROC） was 0. 98. Conclusion CTF guided PTNB can be used as one of the primary examination modalities for lung GGO examination with moderate sensitivity and specificity.

关 键 词：肺活检 磨玻璃样病变 CT 透视 META分析 

分 类 号：R734.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]