胃印戒细胞癌临床病理特点的分析  

Clinicopathological characteristics analysis of gastric signet ring cell carcinoma

作　　者：聂爱英[1] 梁丽娟[1] 雷超[1] 吴琼[1] 时永全[1] 

机构地区：[1]第四军医大学西京医院消化病院肿瘤生物学国家重点实验室,陕西西安710032

出　　处：《现代肿瘤医学》2017年第6期914-917,共4页Journal of Modern Oncology

基　　金：国家自然科学基金项目(编号:81270445;81470805)

摘　　要：目的:通过对胃印戒细胞癌和非印戒细胞癌患者病例资料的对比,了解胃印戒细胞癌的临床病理特点。方法:回顾性分析2000年1月至2014年12月间第四军医大学附属西京医院经术后病理确诊的5 481例胃癌患者的病例资料,根据组织学分型将其分为印戒细胞癌组和非印戒细胞癌组,对两组患者的临床病理资料进行对比分析。结果:印戒细胞癌与非印戒细胞癌在年龄、性别、肿瘤位置及大小、TNM分期、浸润深度、淋巴结转移情况上存在差异(P<0.05),在远处转移方面无显著差异(P>0.05)。早期胃印戒细胞癌的淋巴结转移率高于非印戒细胞癌。结论:胃印戒细胞癌多发生于年轻女性患者,好发部位以胃中下1/3部位多见,早期即可出现较高的淋巴结转移率。Objective： To analyze the clinicopathological characteristics of patients with signet ring cell carcinoma（ SRC） in comparison with non- signet ring cell carcinoma（ NSRC） of the stomach. Methods： The clinicopathological characteristics were reviewed in 5 481 patients with gastric cancer who received surgical resection and pathologically confirmed from January 2000 to December 2014 in Xijing Hospital. The patients were divided into signet ring cell carcinoma（ SRC） and non- signet ring cell carcinoma（ NSRC）,the clinicopathological data of two groups were analyzed.Results： Significant differences were noted in age,gender,tumor location and diameter,TNM classification,invasion depth and lymph node metastasis between SRC and NSRC（ P〈0. 05）,while there were no differences in distant metastasis（ P〉0. 05）. The lymph node metastasis of early signet ring cell carcinoma was higher than non- signet ring cell carcinoma. Conclusion： Signet ring cell carcinoma happens more common in young females. Most carcinoma site locates at middle and lower part of gastric body. Early SRC tends to occur higher lymph node metastasis.

关 键 词：胃癌 早期胃癌 印戒细胞癌 临床病理特点 

分 类 号：R735.2[医药卫生—肿瘤]