头颈部肿瘤病理组织学二次转化的临床启示  

Clinical Enlightenment of Twice Transformation of Head and Neck Tumor Histopathology

作　　者：陈雪姣[1] 张孟伟[2] 仓顺东[1] 

机构地区：[1]郑州大学人民医院/河南省人民医院肿瘤科,河南郑州450003 [2]河南大学淮河医院肿瘤科,河南开封475001

出　　处：《中国继续医学教育》2017年第2期76-77,共2页China Continuing Medical Education

摘　　要：头颈部肿瘤虽然在国外发病率较低,但在我国发病率却远高于欧美国家,尤其是在云南、广东等地区的肿瘤发病谱中,占有一定比例。又因头颈部肿瘤的局部侵犯性强,复发率高,致使该类病种的患者丧失生存信心;特别是复发的局部侵犯较重的晚期患者,由于解剖结构的局限,多数已丧失再次手术的机会,而二线化疗机体敏感度及耐受性均下降,且肿瘤负荷较大导致皮肤溃烂、感染、营养、疼痛等并发症的出现,诸多棘手问题困扰着病患及临床医师,所以寻找新的治疗突破点迫在眉睫。本文就临床诊治中发现头颈部肿瘤存在二次病理组织转化的现象及治疗予以总结。Despite the low incidence of head and neck neoplasms in western countries, but the incidence in China was much higher than Europe and the United States, especially in Yunnan, Guangdong and other regions of the spectrum of tumor. Because of the severely local invasion andrecurrence rate; most of the patients lost the survival faith; Limitations of the anatomical structure, Majority of patients have lost the chance of re-operation with locallyrecurrent of the tumor, thebody sensitivity and tolerance will be decreased in second-line chemotherapy, and thelargertumor load leadto skin ulceration, infection, nutrition, pain and other complications plaguing thepatients and clinicians, so looking for new treatment breakthrough is imminent. In this paper, wesum up theclinical diagnosis and treatment of head and neck cancer found in the existence of secondary pathological changes.

关 键 词：头颈部肿瘤 病理组织学 转化 

分 类 号：R361[医药卫生—病理学]