基于胃主通降理论探讨胃食管反流病症状的产生  

Discussion of gastroesophageal reflux disease based on the theory of stomach unobstruction and descending

作　　者：尹晓岚 王凤云[2] 陈婷[1] 马祥雪 田亚欣 段园志 

机构地区：[1]北京中医药大学研究生院 [2]中国中医科学院西苑医院脾胃病科 [3]北京中国中医科学院研究生院

出　　处：《环球中医药》2017年第2期170-173,共4页Global Traditional Chinese Medicine

基　　金：北京市科委科研基金资助项目(Z141100002214012)

摘　　要：胃食管反流病(gastroesophageal reflux disease,GERD)与中医学"吐酸""食管瘅"等病相类似,基于中医古籍研究及胃腑本身生理病理特点,多数医家认为GERD的主要病机为胃失和降,其与GERD的典型症状、不典型症状及食管外症状的产生密切相关。临床上以"通降法"为原则治疗GERD往往能够收效,相关的基础研究也已阐明通降胃气类中药可能参与调控GERD症状产生机制。全文着眼于从胃主通降的角度阐释GERD症状产生机制,以期进一步为中医药治疗和改善GERD临床症状提供理论支持。The clinical symptoms of gastroesophageal reflux disease（ GERD） correspond to＂acid regurgitation＂＂pyretic abundance of esophageal ＂in Chinese medicine. Through the investigation of Chinese medicine ancient books and pathophysiology of gastric,most clinicians of Chinses medicine think that stomach qi rising can induce the typical symptoms,a typical symptoms and extraesophageal symptoms of GERD. Treatment based on the principle of ＂dredging and descending method＂can take effects,related research has also been elucidated that dredging and descending stomach qi medicine may be involved in the regulation mechanism of GERD symptoms. This paper is from the view of stomach dredging and descending to provide the theory support for the treatment and improvement of the symptoms of GERD in clinical treating.

关 键 词：胃食管反流病 胃主通降 吐酸 通降法 

分 类 号：R573[医药卫生—消化系统]