基于CiteSpace的国内外精准医学研究热点与前沿分析  

CiteSpace-based analysis of hot spots and frontiers in domestic and foreign precision medicine

作　　者：戴阿咪 常青云[2] 杜然然[1] 孙晓北[1] 魏晓瑶 高东平[1] 

机构地区：[1]中国医学科学院医学信息研究所,北京100020 [2]海军总医院信息科,北京100048

出　　处：《中华医学图书情报杂志》2017年第2期14-17,共4页Chinese Journal of Medical Library and Information Science

基　　金：中国医学科学院医学健康科技创新工程经费资助;重大协同创新项目"医学大数据信息采集和分析评估"资助(2016-I2M-2-004)

摘　　要：目的:探讨国内外精准医学研究热点与研究前沿。方法:利用文献计量方法结合信息分析可视化工具CiteSpace分析CNKI和WOS收录的精准医学相关文献作为数据来源。结果:本文所指的精准医学包括个体化医疗、个性化医疗等概念,国内精准医学起步于1992年,2010年起学者对其研究兴趣逐渐增强;国际起步于1985年,从2006年起相关研究逐渐增加,且呈较快增长趋势;国内"精准医学"精准医疗节点最大,基因突变、美国总统奥巴马(精准医学计划)、个性化医疗、基因芯片、基因组学、药物基因组学突现值较高;国际personalized medicine、cancer、breast-cancer节点最大,precision medicine、pharmacogenetics、pharmacogenetics的突现值较高。结论:近期国内外探讨美国总统奥巴马的"精准医学计划"的相关文献数量陡增,药物基因组学是共同研究前沿,国际在肿瘤方面关注度较多。Objective To analyze the hot spots and frontiers in domestic and foreign precision medicine with CiteSpace. Methods The CNKI and WOS-covered papers on precision medicine were analyzed by bibliometries combined with CiteSpace. Results Domestic precision medicine got off in 1992 and scholars became interested in it from 2010. Foreign precision medicine started in 1985 and studies on it increased rapidly from 2006. The node of precision medicine was the largest in China with a rather high value of gene mutation, US president Barack Obama （precision medicine program） , personalized medicine, gene chip, genomics and pharmacogenomics whereas the node of personalized medicine, cancer and breast cancer was the largest with a rather high value of precision medi- cine, pharmacogenomics and pharmacogenetics. Conclusion The number of domestic and foreign papers on US president Barack Obama （precision medicine program） is rapidly increased and pharmacogenomics is their common frontier. However, cancer is highly concerned in foreign countries.

关 键 词：精准医学 CITESPACE 文献计量学 可视化 

分 类 号：R-05[医药卫生] G250.252[文化科学—图书馆学]