轻度阿尔茨海默病日常生活能力及影响因素分析  

Analysis on daily life ability and influence factors of Alzheimer's disease

作　　者：李强[1] 张玉莲[2] 林翠茹[2] 郭家奎[2] 崔远武[2] 刘爽[2] 顾耘[3] 吴迪[4] 

机构地区：[1]天津中医药大学,天津300193 [2]天津中医药大学第二附属医院,天津300150 [3]上海中医药大学附属龙华医院,上海200032 [4]天津市环湖医院,天津300060

出　　处：《天津中医药》2017年第2期106-109,共4页Tianjin Journal of Traditional Chinese Medicine

基　　金：国家重点基础研究(973计划)发展计划项目(2010CB530405)

摘　　要：[目的]轻度阿尔茨海默病日常生活能力及影响因素分析。[方法]收集144例阿尔茨海默病早期患者的日常生活能力量表资料,对量表分项进行因子分析降维处理,研究其日常生活能力特点并进行相关性分析。[结果]1)轻度阿尔茨海默病日常生活能力主要以"处理自己钱财"、"逛街与购物"、"自己搭公共车辆"等工具性生活能力下降为主。2)因子分析共获得5个亚组症状,分别为使用工具、生活自理、室内活动、日常生活、饮食。3)相关性分析发现使用工具、生活自理、日常生活与早期认知损害有密切相关性;使用工具、生活自理、室内活动与年龄也有密切相关性;日常生活能力与早期精神行为异常关系不密切。[结论]轻度阿尔茨海默病主要以工具性生活能力下降为主要特征,认知功能损害、年龄增加等都是影响日常生活能力的因素。加强对轻度痴呆患者日常生活能力的认识,可以为早期临床诊断提供一定的帮助,还可为家庭照料者提供更明确的指导。[Objective] To explore the daily life ability and influence factors of Alzheimer’s disease. [Methods] Factor analysis is used in the scale of research, the purpose is to study the clinical characteristics of daily life ability. [Results] 1）The declining of daily life ability of mild Alzheimer’s disease is mainly about “to deal with their own money”, “shopping ”, “ taking public vehicles by themselves”. 2） Five subgroups were received through factor analysis, including “using tools”, “self-reliance”, “indoor activities”, “daily life and diet”. 3）“Using tools”,“self-reliance”and“daily life and diet”have close correlation with the early cognitive impairment.“Using tools”,“self-reliance” and “indoor activities” also have close correlation with age. Daily life ability is not correlated with the early mental behavior. [Conclusion] Instrumental in life is the main performance of the mild Alzheimer’s patients, and cognitive impairment, increasing age can affect daily life ability. Knowing the mild dementia patients daily life ability, can provide certain help for early clinical diagnosis, and also provide more specific guidance for family caregivers.

关 键 词：阿尔茨海默病 日常生活能力 影响因素 

分 类 号：R749.16[医药卫生—神经病学与精神病学]