脑心动脉粥样硬化易患因素分析及脑心通胶囊的干预研究  

Risk Factors of Brain-Heart Atherosclerosis and Effect of Naoxintong Capsules

作　　者：李辉[1] 

机构地区：[1]邢台医学高等专科学校,河北邢台054000

出　　处：《辽宁中医杂志》2017年第2期301-303,共3页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的:探讨脑心动脉粥样硬化的中医证型间易患因素的关系和血脂与本病的关系及脑心通胶囊的干预研究,为中医诊断和辨证施治提供客观依据,以更好地服务于临床。方法:400例患者以EXCEL表格的形式录入患者信息,采用问卷调查的方式,对患者的姓名、性别、年龄、身高、体重等一般资料进行记录,对心系证候证候、全身证候、饮食口味相关证候、舌、脉象等信息进行采集;对其中气虚血瘀证患者加服脑心通胶囊治疗,疗程4周,观察症状积分及血脂变化。结果:以计数资料进行统计。结果有效病例392例,脑心动脉粥样硬化的中医证型分布情况,痰瘀互结型、肝肾阴虚型、气虚血瘀型、脾虚湿盛型(按频次统计由多到少排列)。各证型平均年龄组间没有显著差异(P>0.05)。痰瘀互结组与气虚血瘀组组间比较有显著差异(P<0.05);其余各组间比较均无显著差异(P>0.05)。各证型血脂组间两两比较,无显著差异(P>0.05)。用步长脑心通胶囊干预4周后,气虚血瘀型脑心动脉粥样硬化患者症状明显改善,差异有统计学意义(P<0.05);血脂水平明显降低,比较有统计学意义(P<0.05)。结论:中医药如能干预脑心动脉粥样硬化效果会十分理想,但需要建立统一的辨证论治标准体系,规范中医治疗。Objective ： To investigate the intervention of Naoxintong Capsules on brain - heart atherosclerosis and the relation- ships among TCM risk factors of different syndromes to provide an objective basis for Chinese medicine diagnosis and therapy in order to better clinical services. Methods：A total of 400 patients＇ information was input to the EXCEL form. By the use of question- naires, general data was recorded, including name, gender, age, height, weight, heart syndromes, systemic syndromes, tastes related syndromes,tongue,pulse and other information. Patients with Qi deficiency and blood stasis added Naoxintong Capsules for 4 weeks and blood lipids were observed. Results：There were 392 cases effective. The distribution of TCM syndromes from more to less ： phlegm and blood stasis type, liver - kidney Yin deficiency, Qi deficiency and blood stasis, spleen deficiency and excess dampness. There was no significant difference （ P 〉 0. 05 ） between the average age of the syndrome groups. Phlegm and stasis group and Qi deficiency and blood stasis group had significant difference （P 〈 0.05 ）. Among other groups, it showed no signifi- cant difference （ P 〉 0. 05 ）. Lipid comparison had no significant difference （ P 〉 0. 05 ）. After using Naoxintong Capsules inter- vention for 4 weeks, symptoms of Qi deficiency and blood stasis sydrnome of brain - heart atherosclerosis were improved signifieantly and the difference was statistically significant （ P 〈 0. 05 ）. The blood lipid levels were significantly lower（ P 〈 O. 05 ）. Con- clusion ： Chinese medicine for brain - heart atheroselerosis can aehieve good effect but we need to establish a unified system of di- agnosis and treatment standards to make traditional Chinese medicine treatment norm.

关 键 词：脑心动脉粥样硬化 易患因素 脑心通胶囊 

分 类 号：R743.1[医药卫生—神经病学与精神病学]