吸烟与帕金森病嗅觉障碍  

Relationship between smoking and olfactory dysfunction in Parkinson's disease

作　　者：曹明[1] 陈彪[1] 

机构地区：[1]首都医科大学宣武医院神经内科,北京100053

出　　处：《中国现代神经疾病杂志》2017年第2期101-104,共4页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：国家高技术研究发展计划(863计划)项目(项目编号:2012AA02A514)~~

摘　　要：帕金森病是临床常见的神经变性病,根据临床症状可以分为运动症状和非运动症状,嗅觉障碍作为帕金森病最常见的非运动症状越来越受到重视。既往研究显示,尼古丁可能降低帕金森病发病风险,而有吸烟史的帕金森病患者嗅觉障碍轻微,因此吸烟可能通过嗅觉系统对帕金森病产生保护作用。吸烟对帕金森病患者嗅觉功能的影响可能有助于我们更全面地了解帕金森病发病过程。Parkinson＇s disease（PD） is a common neurodegenerative disease.It is characterized by acombination of motor symptoms and non-motor symptoms（NMS） based on clinical symptoms.More andmore attention has been drawn to olfactory dysfunction as an early NMS in PD.It is believed that nicotinein cigarettes may lower the risk of getting PD and people with smoking history may have lower risk ofolfactory dysfunction.So smoking may have protective effect on PD.The effect of smoking on olfactoryfunction in PD patients may lead us to have a better understanding of the pathogenesis of PD.

关 键 词：吸烟 帕金森病 嗅觉障碍 综述 

分 类 号：R742.5[医药卫生—神经病学与精神病学]