中药辅助治疗急性胰腺炎的临床疗效观察  

Observation of clinical effect by traditional Chinese medicine in adjuvant therapy for acute pancreatitis

作　　者：邱嘉华[1] 陈丽[1] 谢小月[1] 

机构地区：[1]深圳市龙华新区人民医院消化内科(南方医科大学附属医院),518000

出　　处：《中国实用医药》2017年第1期40-42,共3页China Practical Medicine

摘　　要：目的研究中药辅助治疗急性胰腺炎的临床疗效。方法 64例急性胰腺炎患者,随机分成对照组和治疗组,各32例。对照组给予禁食、持续肠胃减压、抑酸、抑制胰腺分泌、防治水电解质紊乱等内科综合治疗;治疗组在对照组内科综合治疗的基础上给予中药胃管内注入或口服。观察两组患者的临床治疗效果,并于治疗前后比较两组血清C反应蛋白(CRP)、白细胞介素-6(IL-6)、白细胞介素-10(IL-10)等水平。结果治疗组治疗总有效率为90.63%,高于对照组的68.75%,差异具有统计学意义(P<0.05)。治疗前,两组患者血清CRP、IL-6、IL-10水平比较差异均无统计学意义(P>0.05)。治疗后,两组胰腺炎患者血清CRP、IL-6、IL-10均较治疗前显著下降,且治疗组下降更明显,差异有统计学意义(P<0.05)。结论中药辅助常规内科综合治疗急性胰腺炎能快速清除炎症因子,起到多靶点干预治疗的作用,提高了临床疗效,值得临床推广。Objective To research clinical effect by traditional Chinese medicine in adjuvant therapy for acute pancreatitis. Methods A total of 64 patients with acute pancreatitis were randomly divided into control group and treatment group, with 32 cases in each group. The control group received internal medical comprehensive treatment by abrosia, continuous gastrointestinal decompression, acid inhibition, pancreatic secretion inhibition, and water and electrolyte disturbance prevention. The treatment group received additional traditional Chinese medicine by stomach tube injection or oral administration to internal medical comprehensive treatment in the control group. Observation was made on clinical effects in the two groups. Serum C-reactive protein（CRP）, interleukin-6（IL-6） and interleukin-10（IL-10） levels before and after treatment were compared between the two groups. Results The treatment group had higher total effective rate as 90.63% than 68.75% in the control group, and their difference had statistical significance（P〈0.05）. Before treatment, there was no statistically significant difference of serum CRP, IL-6 and IL-10 levels between the two groups（P〉0.05）. After treatment, both groups had obviously lower serum CRP, IL-6 and IL-10 levels than those before treatment, and the treatment group had much more obvious decreasing levels. Their difference had statistical significance（P〈0.05）. Conclusion Traditional Chinese medicine in adjuvant therapy for acute pancreatitis can rapidly eliminate inflammatory factor and provide multiple targeted prevention and treatment effect, along with improved clinical effect. This method is worth clinical promotion.

关 键 词：急性胰腺炎 白细胞介素-6 白细胞介素-10 中药 内科综合治疗 

分 类 号：R576[医药卫生—消化系统]