橄榄脑桥小脑萎缩十字征的演变及诊断价值  

Development of the cross sign of olivepontocerebellar atrophy and its diagnostic value

作　　者：李淑英 姚丽英 姚丁 罗艳春 

机构地区：[1]乌兰察布市中心医院神经内科,内蒙古自治区乌兰察布012000 [2]乌兰察布市中心医院CT室,内蒙古自治区乌兰察布012000

出　　处：《中国基层医药》2017年第4期547-549,I0004,共4页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的：探讨橄榄脑桥小脑萎缩（OPCA）十字征的演变及诊断价值。方法回顾性分析8例OPCA 患者的临床及影像学资料。MRI 成像采用 SE 序列，平扫 T1 WI、T2 WI，轴位，冠状位，矢状位成像。结果8例患者均隐袭性起病，临床表现以小脑共济失调及自主神经障碍为主。影像学阳性所见符合临床表现，主要为脑干萎缩，8例患者均有此表现，其次为小脑萎缩，其中6例患者为对称性萎缩，2例为非对称性萎缩。6例患者在发病后1．5～3年出现典型十字征。结论十字征在 OPCA 发展到一定阶段逐渐出现，特异性较高。故临床表现和磁共振成像结合，对 OPCA 的诊断和鉴别诊断有重要价值。Objective To explore the development of the cross sign of olivepontocerebellar atrophy（OPCA） and its diagnostic value.Methods The clinical and imaging data of 8 patients with OPCA were analyzed retrospec-tively.MRI imaging used SE sequence,plain T1 WI,T2 WI,axial,coronal,sagittal imaging.Results All patients were hide onset.The major clinical presentation was cerebellar atsxia and autonomic nerve dysfunction.Positive radiographic findings were consistent with clinical presentation,mainly for the brain stem atrophy,8 patients of the group had this performance,followed by cerebellar atrophy,6 patients had symmetrical atrophy and 2 patients had asymmetric atro-phy.6 patients after onset of 1.5 -3 years showed a typical cross.Conclusion The cross sign gradually appears at a certain stage of development,and it has high specificity.So the combination of clinical and MRI is valuable for the diagnosis and differential diagnosis of OPCA.

关 键 词：橄榄体脑桥小脑萎缩 磁共振成像 十字征 多系统萎缩 

分 类 号：R742[医药卫生—神经病学与精神病学]