新疆维吾尔族人群与NAFLD的相关危险因素分析  

Analysis of related risk factors of non-alcoholic fatty liver disease in Xinjiang Uygur population

作　　者：阿迪拉.阿地江 林玉婷 蔡雯[3] 姚华[1] 

机构地区：[1]新疆医科大学公共卫生学院劳动与环境卫生教研室,乌鲁木齐830011 [2]新疆维吾尔自治区妇幼保健医院检验科,乌鲁木齐830001 [3]新疆医科大学护理学院,乌鲁木齐830099

出　　处：《重庆医学》2017年第7期943-945,共3页Chongqing medicine

基　　金：国家自然科学基金资助项目(81460120)

摘　　要：目的探讨新疆地区维吾尔族人群非酒精性脂肪性肝病(NAFLD)的相关危险因素。方法收集新疆医科大学第一附属医院新入院维吾尔族患者及新疆医科大学体检中心维吾尔族健康体检者共966例,进行问卷调查及血生化和B超检查,依据体检情况分为NAFLD组(569例)和非NAFLD组(397例);按照体质量指数(BMI)和腰围身高比值(WHtR)分层对NAFLD组进行危险因素的相关性分析。结果两组对象BMI、WHtR比较,差异有统计学意义(P<0.05);超重(OR=2.527,P<0.05)和肥胖(OR=1.938,P<0.05)是NAFLD的危险因素。多因素Logistic回归分析显示:BMI、空腹血糖(FPG)和三酰甘油(TG)与NAFLD有关(P<0.05),是NAFLD的危险因素。结论BMI、WHtR、FPG和TG是NAFLD的危险因素,在评价和预测NAFLD的高危人群中具有一定的临床意义。Objective To explore the related risk factors of non-alcoholic fatty liver disease（NAFLD）in Uygurs population of Xinjiang area.Methods A total of 966 Uygurs individuals undergoing physical examination in the First Affiliated Hospital and physical examination center of Xinjiang Medical University were collected and performed the questionnaire investigation,blood biochemical detection and B-type ultrasound examination;the subjects were divided into the NAFLD group（569cases）and nonNAFLD group（397cases）according to the physical examination situation.The NAFLD group was performed the correlation analysis of risk factors according to the body mass index（BMI）and waist to height ratio（WHtR）stratification.Results BMI and WHtR had statistical difference between the two groups（P〈0.05）;overweight（OR=2.527,P〈0.05）and obesity（OR=1.938,P〈0.05）were the risk factors of NAFLD.The multivariate Logistic regression analysis showed that BMI,fasting plasma glucose（FPG）and triacylglycerol（TG）were associated with NAFLD（P〈0.05）and the risk factors of NAFLD.Conclusion BMI,WHtR,FPG and TG are the risk factors of NAFLD,and have a certain clinical significance in the evaluation and prediction of NAFLD high risk population.

关 键 词：非酒精性脂肪性肝病 维吾尔族 人体质量指数 危险因素 

分 类 号：R575[医药卫生—消化系统]