西吡氯铵含漱液联合康复新液治疗正中菱形舌炎的效果  

Treatment of cetylpyridinium chloride gargarism combined with Kangfuxin on median rhomboid glossitis

作　　者：武霖[1] 杨珺[2] 

机构地区：[1]江苏大学附属人民医院口腔科,江苏镇江212002 [2]江苏大学附属人民医院检验科,江苏镇江212002

出　　处：《中国医药导报》2017年第4期98-101,共4页China Medical Herald

摘　　要：目的观察西吡氯铵含漱液联用康复新液治疗正中菱形舌炎的临床疗效。方法选择2014年9月~2016年7月于江苏大学附属人民医院就诊并诊断为正中菱形舌炎的患者35例,按照随机数字表随机分为两组,治疗组(n=19)给予西吡氯铵含漱液和康复新液,对照组(n=16)给予西吡氯铵含漱液。比较两组患者自觉症状、白色念珠菌检出率(刮舌涂片镜检、唾液真菌培养阳性率)的差异。结果基线分析表明治疗前两组资料指标具有可比性。两组治疗后自觉症状阳性率均有较大改善,但治疗组改善幅度大于对照组,差异有统计学意义(P<0.05)。两组治疗后白色念珠菌检出率均有较大改善,但治疗组改善幅度大于对照组;治疗组与对照组在治疗期间均未发生明显不良反应。结论西吡氯铵含漱液联用康复新液治疗正中菱形舌炎有确切疗效,对患者的自觉症状、白色念珠菌检出率均有明显改善,且未发现明显不良反应。Objective To observe the clinical efficacy of cetylpyridinium chloride gargarism combined with Kangfuxin on median rhomboid glossitis. Methods 35 patients diagnosed with median rhomboid glossitis by Affiliated People＇s Hospital of Jiangsu University from September 2014 to July 2016 were included,and divided into two groups in random by random number table.The treatment group（n=19） was given cetylpyridinium chloride gargarism and Kangfuxin,mean-while the control group （n=16） was treated with cetylpyridinium chloride gargarism only.Compared the differenc, es of positive rate in rational symptom, smear microscopic examination and saliva fungus cultivation. Results Baseline analy- sis indicated that the two groups were comparable before treatment. The positive rate of rational symptoms in two groups were both improved after treatment, while the improving range in treatment group was larger than that in control group, and the difference was statistically signifieant（P 〈 0.05）.The detection rate of Candida albicans were both signifi- cantly improved after treatment in the two groups, but the improving range in treatment group was larger than that in control group.No obvious adverse reaction was found during treatment. Conclusion Combination of cetylpyridinium chloride gargarism with Kangfuxin shown curative effect on median rhomboid glossitis,and obviously decreased the rational symptom and detection rate of Candida albicans, while no obvious adverse reaction was found during treatment.

关 键 词：正中菱形舌炎 西吡氯铵 康复新液 白色念珠菌 

分 类 号：R781.5[医药卫生—口腔医学]