金银花精油及其与β-环糊精包合物的制备工艺研究  

Study on the Preparation Processes of Honeysuckle Essential Oil and Its Inclusion Compound with β-cyclodextrin

作　　者：林玉环[1] 高昆[1] 况鹏群[1] 井文华[1] 王敏敏[1] 赵玉萍[1] 

机构地区：[1]山东省鲁南中药材工程技术研究中心,临沂大学,山东临沂276000

出　　处：《安徽农业科学》2017年第5期67-69,共3页Journal of Anhui Agricultural Sciences

基　　金：大学生创新创业训练计划项目(201510452026);山东省重点研发计划项目(2015GNC110036)

摘　　要：[目的]优选金银花精油及其与β-环糊精包合物的制备工艺。[方法]采用水蒸气蒸馏法制备金银花精油,用GC-MS分析金银花精油的主体呈香成分及含量;采用饱和水溶液法,通过正交试验设计,以金银花精油的包合率为指标,考察金银花精油与β-环糊精的包合比例、包合温度、搅拌时间和烘干温度对金银花精油-β-环糊精包合物制备工艺的影响。[结果]水蒸气蒸馏法制备金银花精油的得率为0.12%,经GC-MS分析,金银花精油的主体呈香成分为单萜和倍半萜类化合物,占金银花精油含量的75.30%,其中,金银花精油中芳樟醇及其衍生物含量大于25.60%;最佳金银花精油-β-环糊精包合物制备工艺条件为金银花精油与β-环糊精的包合比例1∶10(m L∶g)、包合温度60℃、搅拌时间3 h、烘干温度45℃,在此最优条件下,金银花精油的包合率为68.95%。[结论]水蒸气蒸馏法和饱和水溶液法可分别用于金银花精油及其与β-环糊精包合物的制备。[ Objective ] To optimize the preparation processes for honeysuckle essential oil and its inclusion compound with β-cyclodextrin. [ Method ] Honeysuckle essential oil was prepared with steam distillation method, the composition and content of principal aroma components of the honeysuckle essential oil were analyzed with GC-MS. Honeysuckle essential oil-β-cyclodextrin inclusion compound was prepared with satu- rated water solution method, and the inclusion rate of honeysuckle essential oil was used as evaluation index to investigate the influences of the proportion of honeysuckle essential oil and β-cyclodextrin, the inclusion temperature, the stirring time and the drying temperature on the prep- aration process of the inclusion compound with orthogonal test. [ Result] The yield of honeysuckle essential oil prepared by steam distillation method was 0.12% , after analysis with GC-MS, the principal aroma components of the honeysuckle essential oil were monuterponoids and ses- quiterpenoids, and the total content of these two kinds of compounds was 75.30%. Among them, the content of linalool and its derivatives in honeysuckle essential oil was more than 25.60%. The optimum preparation process conditions for honeysuckle essential oil-β-cyclodextrin in- clusion compound were as follows： the proportion of honeysuckle essential oil and β-cyclodextrin was 1： 10（ mL： g）, the inclusion temperature was 60 ℃ , the stirring time was 3 h and the drying temperature was 45 ℃. Under the optimum conditions, the inclusion rate of honeysuckle essential oil was 68.95%. [ Conclusion] The steam distillation method and the saturated water solution method can be respectively used for the preparation of honeysuckle essential oil and its inclusion compound with β-cyclodextrin.

关 键 词：金银花精油 水蒸气蒸馏法 Β-环糊精 包合物 正交试验 

分 类 号：TQ461[化学工程—制药化工]