绷带式角膜接触镜对Epi-LASIK术后角膜上皮修复的研究  

Study of bandage contact lens on cornea epithelial healing after Epi-LASIK

作　　者：宋碧英[1] 白继[1] 张燕[1] 邓小丽[1] 唐文[1] 姜姝[1] SONG Bi-ying BAI Ji ZHANG Yan DENG Xiao-li TANG Wen JIANG Shu(Department of Ophthahnology,Institute of Sur- gery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, Chin)

机构地区：[1]第三军医大学大坪医院野战外科研究所眼科专科医院,重庆400042

出　　处：《局解手术学杂志》2017年第3期212-214,共3页Journal of Regional Anatomy and Operative Surgery

摘　　要：目的观察绷带式角膜接触镜对Epi-LASIK术后角膜上皮修复的影响,评价其安全性和有效性。方法前瞻性病例对照研究。选取92例(181眼)接受Epi-LASIK的患者,随机分为2组,对照组46例(91眼)患者Epi-LASIK术后给予常规眼科护理;观察组46例(90眼)患者给予常规眼科护理,并给予绷带式角膜接触镜。术后随访1周,定期观察2组患者术后视力、疼痛反应和角膜上皮修复时间情况。结果 Epi-LASIK术后,2组患者视力恢复差异无统计学意义(P>0.05);Epi-LASIK术后第1天、第3天和第7天,观察组疼痛评分分别为(2.53±0.62)、(1.39±0.71)、(0.07±0.25),对照组疼痛评分分别为(3.22±0.79)、(1.74±0.49)、(0.26±0.49),观察组疼痛评分轻于对照组,差异具有统计学意义(P<0.05)。Epi-LASIK术后观察组角膜创伤修复平均时间为(2.80±0.86)d,对照组角膜创伤修复平均时间为(4.07±0.68)d,观察组术后角膜创伤修复的平均时间较对照组短,差异具有统计学意义(P<0.05)。结论 Epi-LASIK术后应用绷带式角膜接触镜能够减轻患者术后疼痛,促进近视术后患者的创伤角膜修复,具有较强的临床实用价值。Objective To observe the effect of bandage contact lens on cornea epithelial healing after Epi-LASIK, and to evaluate the efficacy and safety. Methods Prospective case-control study. The 92 cases（ 181 eyes） performing Epi-LASIK were devided into observation group and control group. The 46 cases （91 eyes） of the control group were covered with routine nursing and the other 46 cases （90 eyes） of the observation group were served with bandage contact lens after Epi-LASIK. The symptoms and signs, time of corneal epithelial recovery, visual acuity and pain of postoperation of the two groups were examined within one week. Results After Epi-LASIK treatment, there was no significant difference in visual acuity between the two groups（P 〉 0.05 ）. At the 1st, 3r d, and 7th day after Epi-LASIK treatment, the ache grading results of the observation group were （2.53±0.62） , （ 1.39±0.71 ） , （0.07 ±0.25） ; and the ache grading results of control group were （ 3.22 ± 0.79 ）, （ 1.74± 0.49 ）, （ 0.26 ±0.49 ）. Pain scores of observation group were significantly lighter than that of the control group （ P 〈 0.05 ）. After Epi-LASIK treatment, the average time of corneal wound healing in the observation group and control group were （ 2.80 ± 0.86） days and （4.07 ± 0.68 ） days respectively. The average time of postoperative corneal wound healing in the observation group was shor- ter than control group （ P 〈 0.05 ）. Conclusion The application of bandage contact lens on cornea epithelial healing after Epi-LASIK treatment can reduce the pain of patients and promote the recovery of cornea in myopia patients.

关 键 词：机械法准分子激光上皮瓣下角膜磨镶术 绷带式角膜接触镜 疼痛 角膜上皮修复 

分 类 号：R778[医药卫生—眼科]