玻璃体切除联合C_3F_8填充治疗黄斑裂孔的疗效观察  

Vitrectomy and C_3F_8 tamponade for macular hole

作　　者：唐晶[1] 万宇[1] 黄海[1] 樊宗山[1] 何艺岚 Tang Jing Wan Ning Huang Hai Fan Zongshan He Yilan(Second Clinical College of North Sichuan Medical College, Nanchong 637000, Chin)

机构地区：[1]川北医学院第二临床医学院南充市中心医院,四川南充637000

出　　处：《临床眼科杂志》2017年第1期15-17,共3页Journal of Clinical Ophthalmology

摘　　要：目的探讨玻璃体切除联合C_3F_8填充治疗黄斑裂孔的临床效果。方法选择2013年11月至2014年11月期间我院收治的50例黄斑裂孔患者为研究对象,根据入院编号的偶数和奇数将其分为两组,两组均行玻璃体切除术,其中给予对照组空气填充,而观察组则应用C_3F_8填充治疗,对两组的手术效果进行对比分析。结果术前,两组矫正视力比较无明显差异(P>0.05);术后1个月、6个月,相比较对照组而言,观察组的矫正视力改善明显,组间对比差异显著(P<0.05);与对照组比较,观察组的术后并发症发生率明显较低,但是组间对比无显著差异(P>0.05);同时,两组的Gass分期Ⅱ期、Ⅲ期、Ⅳ期裂孔闭合率比较差异有统计学意义(P<0.05)。结论玻璃体切除联合C_3F_8填充治疗黄斑裂孔,可以使患者的视力得到明显改善,并能提高裂孔闭合率。Objective To study the clinical effects of vitrectomy combined with C3F8 in the treatment of macular hole. Methods 50 cases of macular hole were selected from our hospital between November 2013 and November 2014.All patients received vitrectomy and either air filling（ control group） or C3F8 filling. Clinical outcomes of the two groups were compared and analyzed. Results Before operation,corrected visual acuity were similar between the two groups. At 1month and 6 months after surgery,patients treated with vitrectomy and C3F8 tamponade had significantly better corrected visual acuity（ P〈0. 05）; postoperative complications were significantly less. Closure rate for GASS stage II,III and IV macula hole were significantly better in patients received C3F8. Conclusions The clinical application of C3F8 combined with vitrectomy in the treatment of macular hole can improve visual acuity and closure rate.

关 键 词：玻璃体切除 黄斑裂孔 C3F8 临床效果 

分 类 号：R779.6[医药卫生—眼科]