抗青光眼手术后滤过泡渗漏的研究进展  

Research progress for filtering blebs leakage after anti-glaucoma surgery

作　　者：洪颖[1] 王薇[1] 

机构地区：[1]北京大学第三医院眼科,100191

出　　处：《中华实验眼科杂志》2017年第3期277-281,共5页Chinese Journal Of Experimental Ophthalmology

摘　　要：抗青光眼手术后滤过泡渗漏的发生率为3％-25％。发生滤过泡渗漏的影响因素主要包括抗代谢药物的使用和手术中所采用的结膜瓣的类型，其组织病理学机制主要为结膜下组织变性。滤过泡渗漏可造成低眼压、滤过泡炎甚至眼内炎。目前滤过泡渗漏的治疗方法主要为保守治疗和手术治疗。保守治疗主要包括包扎、自体血清或纤维蛋白注射或点眼、应用组织胶修补等。手术治疗包括自体结膜组织转位或修补，角膜、巩膜、生物羊膜和生物材料修补等。若没有得到及时、有效的治疗，滤过泡渗漏会引起严重并发症；其治疗方法较多，但都有其自身局限性，需要综合考虑，密切随访。Recent researches showed the incidence of filtering blebs leakage after anti-glaucoma surgery was 3% -25%. The affecting factors include the usage of antimetabolite medicine. Pathogenesis of filtering blebs leakage is the basement membrane of conjunctival cells fracture, reduced conjunctival cells and subconjunctival cells. It may cause hypotony, bleb infection and even endoophthalmitis. The treatments mainly include conservative therapy and surgery. Conservative therapy methods include package, autoserum or fibrin injection or eye drops and tissue glue. Surgery methods include eonjunctival transposition, repair with conjunctival, corneal, scleral, amniotic membrane and biomechanical materials. Filtering blebs leakage may induce severve complications without timely treatments. Conservative therapy and surgery have their own limitations, which need to be considered intently and followed up closely.

关 键 词：滤过泡 渗漏 病因学 治疗 

分 类 号：R779.6[医药卫生—眼科]