早期乳腺癌保乳术中低能X线放疗安全及可行性初步研究  

Safety and feasibility of low？energy X？ray radiotherapy in breast conserving surgery for early？stage breast cancer

作　　者：熊英[1] 周伟[1] 黄林平[2] 刘军[2] 

机构地区：[1]中日友好医院放射肿瘤科,北京100029 [2]中日友好医院乳腺外科

出　　处：《中华放射肿瘤学杂志》2017年第3期307-309,共3页Chinese Journal of Radiation Oncology

摘　　要：目的 探讨早期乳腺癌保乳手术中放疗的短期并发症及美容效果.方法 回顾分析2013-2015年间30例早期乳腺癌患者资料.全部患者均行乳腺癌保乳手术及低能X线术中放疗,术中予以适配器表面20Gy处方剂量,术后观察手术区域并发症、放射性损伤、乳房美容效果.结果无严重3、4级不良反应;短期并发症为4例（13%）出现血清肿,其中2例需要外科抽吸处理;3例（10%）出现1—2级乳腺皮肤红斑;美容效果优秀率为50%.患者均未出现LR及远处转移.结论 低能X线术中放疗在乳腺癌保乳手术中安全可行,在部分早期低危乳腺癌患者中可作为瘤床补量的一种选择参考.Objective To investigate the short-term complications and cosmetic outcomes of radiotherapy in breast conserving surgery for early-stage breast cancer. Methods A retrospective analysis was performed on clinical data from 30 patients with early-stage breast cancer from 2013 to 2015. All patients underwent breast conserving surgery combined with intraoperative low-energy X-ray radiotherapy. The prescribed dose was 20 Gy at the surface of the applicator. Local complications, radiation injury, and cosmetic outcomes were observed after surgery. Results No grade 3-4 adverse reactions were found in patients. In terms of short-term complications, four patients （13%） had seroma, two of whom needed suction treatment;three patients （ 10%） had grade 1-2 skin erythema. Half of the patients had excellent cosmetic outcomes. None of the patients had local recurrence or distant metastasis. Conclusions Intraoperative low-energy X-ray radiotherapy is safe and feasible in breast conserving surgery for breast cancer. It can be considered as an optional approach for tumor bed boost in some patients with early-stage low-risk breast cancer.

关 键 词：乳腺肿瘤/术中放射疗法 短期并发症 

分 类 号：R737.9[医药卫生—肿瘤]