干细胞治疗脊髓损伤研究进展  

Progress of Stem Cell Therapy in Spinal Cord Injury

作　　者：陈刚[1,2] 吴骏[2] 祝贺[2] 于天飞[1] 

机构地区：[1]齐齐哈尔大学生命科学与农林学院,齐齐哈尔161006 [2]中国科学院动物研究所干细胞与生殖生物学国家重点实验室,北京100101

出　　处：《中国生物工程杂志》2017年第2期88-92,共5页China Biotechnology

基　　金：国家"973"计划资助项目(2015CB964800)

摘　　要：脊髓损伤后的常规治疗手段是在有效时间内进行手术缓减外力压迫,防止脊髓神经进一步受损。细胞替代治疗理论上可治愈脊髓损伤,不同类型细胞可从各角度产生治疗作用,包括损伤后的脊髓轴突再生、神经元再建和轴突髓鞘化等,进而促进功能恢复。对近年来干细胞治疗脊髓损伤研究中的最新结果进行了概述,以期为干细胞治疗脊髓损伤的研究提供参考。The conventional treatment of spinal cord injury（SCI） is decompressive laminectomy within a given time after SCI to prevent the secondary damage. Theoretically,cell replacement therapy can cure SCI,different types of cells can exert therapeutic effects from various aspects including injured spinal cord axon regeneration,neuron reconstruction and remyelinization, and finally promote the functional recovery. The published literatures in recent years which focusing on stem cell therapy in spinal cord injury were reviewed.

关 键 词：脊髓损伤 干细胞 细胞移植 细胞治疗 

分 类 号：R394.2[医药卫生—医学遗传学]